NAPRT Antibody, HRP conjugated (PACO28495)
- SKU:
- PACO28495
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | NAPRT Antibody, HRP conjugated (PACO28495) |
抗体コード: | PACO28495 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Nicotinate phosphoribosyltransferase protein (1-310AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Catalyzes the conversion of nicotinic acid, (NA) to NA mononucleotide (NaMN). Essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. |
シノニム: | Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21) (FHA-HIT-interacting protein) (Nicotinate phosphoribosyltransferase domain-containing protein 1), NAPRT, FHIP NAPRT1 |
UniProt Protein Function: | NAPRT1: Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN). Essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. Belongs to the NAPRTase family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 6.3.4.21; Transferase Chromosomal Location of Human Ortholog: 8q24.3 Cellular Component: cytosol; extracellular region Molecular Function:nicotinate phosphoribosyltransferase activity; protein binding Biological Process: neutrophil degranulation; response to oxidative stress |
NCBI Summary: | Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q6XQN6 |
NCBI GenInfo Identifier: | 166221824 |
NCBI Gene ID: | 93100 |
NCBI Accession: | Q6XQN6.2 |
UniProt Secondary Accession: | Q6XQN6,Q6PJL1, Q6XQN4, Q6XQN5, Q8N5E8, Q9BRG0, A7BFI3 |
UniProt Related Accession: | Q6XQN6 |
Molecular Weight: | 58kDa |
NCBI Full Name: | Nicotinate phosphoribosyltransferase |
NCBI Synonym Full Names: | nicotinate phosphoribosyltransferase |
NCBI Official Symbol: | NAPRT |
NCBI Official Synonym Symbols: | NAPRT1; PP3856 |
NCBI Protein Information: | nicotinate phosphoribosyltransferase |
UniProt Protein Name: | Nicotinate phosphoribosyltransferase |
UniProt Synonym Protein Names: | FHA-HIT-interacting protein; Nicotinate phosphoribosyltransferase domain-containing protein 1 |
UniProt Gene Name: | NAPRT |