Anti-LGR6 Antibody (CAB7383)
- SKU:
- CAB7383
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-LGR6 Antibody |
抗体コード: | CAB7383 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-510 of human LGR6 (NP_067649.2). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | A-549, Raji |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-510 of human LGR6 (NP_067649.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | ALDL SWNA IRSI HPEA FSTL HSLV KLDL TDNQ LTTL PLAG LGGL MHLK LKGN LALS QAFS KDSF PKLR ILEV PYAY QCCP YGMC ASFF KASG QWEA EDLH LDDE ESSK RPLG LLAR QAEN HYDQ DLDE LQLE MEDS KPHP SVQC SPTP GPFK PCEY LFES W |
遺伝子ID: | 59352 |
Uniprot: | Q9HBX8 |
セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
計算された分子量: | 89kDa/99kDa/104kDa |
観察された分子量: | 104kDa |
同義語: | LGR6, GPCR, VTS20631 |
バックグラウンド: | This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants. |
UniProt Protein Function: | LGR6: a leucine-rich repeat-containing G-protein-coupled receptor. Receptor for R-spondins, potent stimulators of adult stem cell proliferation. A marker of adult stem cells. A Wnt receptor component that enhances Wnt signaling by soluble R-spondin proteins. A marker of a multipotent population of skin stem cells. Three isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Tumor suppressor; Membrane protein, integral Chromosomal Location of Human Ortholog: 1q32.1 Cellular Component: integral to plasma membrane; plasma membrane; trans-Golgi network membrane; vesicle Molecular Function:G-protein coupled receptor activity; protein binding; transmembrane receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of cell migration; positive regulation of Wnt receptor signaling pathway; Wnt receptor signaling pathway |
NCBI Summary: | This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9HBX8 |
NCBI GenInfo Identifier: | 158519993 |
NCBI Gene ID: | 59352 |
NCBI Accession: | Q9HBX8.3 |
UniProt Secondary Accession: | Q9HBX8,Q5T509, Q5T512, Q6UY15, Q86VU0, Q96K69, Q9BYD7 |
UniProt Related Accession: | Q9HBX8 |
Molecular Weight: | 99,295 Da |
NCBI Full Name: | Leucine-rich repeat-containing G-protein coupled receptor 6 |
NCBI Synonym Full Names: | leucine-rich repeat containing G protein-coupled receptor 6 |
NCBI Official Symbol: | LGR6 |
NCBI Official Synonym Symbols: | GPCR; VTS20631 |
NCBI Protein Information: | leucine-rich repeat-containing G-protein coupled receptor 6 |
UniProt Protein Name: | Leucine-rich repeat-containing G-protein coupled receptor 6 |
Protein Family: | Leucine-rich repeat-containing G-protein coupled receptor |
UniProt Gene Name: | LGR6 |
UniProt Entry Name: | LGR6_HUMAN |
View AllClose