Anti-GPCR / LGR6 Antibody (CAB9128)
- SKU:
- CAB9128
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-GPCR / LGR6 Antibody |
抗体コード: | CAB9128 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human GPCR / LGR6 |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Rat |
ポジティブサンプル: | HeLa, MCF7, Rat testis |
免疫原: | A synthesized peptide derived from human GPCR / LGR6 |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 59352 |
Uniprot: | Q9HBX8 |
セルラーロケーション: | |
計算された分子量: | 104kDa |
観察された分子量: | 104KDa |
同義語: | GPCR, VTS20631 |
バックグラウンド: | This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
UniProt Protein Function: | LGR6: a leucine-rich repeat-containing G-protein-coupled receptor. Receptor for R-spondins, potent stimulators of adult stem cell proliferation. A marker of adult stem cells. A Wnt receptor component that enhances Wnt signaling by soluble R-spondin proteins. A marker of a multipotent population of skin stem cells. Three isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Tumor suppressor; Membrane protein, integral Chromosomal Location of Human Ortholog: 1q32.1 Cellular Component: integral to plasma membrane; plasma membrane; trans-Golgi network membrane; vesicle Molecular Function:G-protein coupled receptor activity; protein binding; transmembrane receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of cell migration; positive regulation of Wnt receptor signaling pathway; Wnt receptor signaling pathway |
NCBI Summary: | This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9HBX8 |
NCBI GenInfo Identifier: | 158519993 |
NCBI Gene ID: | 59352 |
NCBI Accession: | Q9HBX8.3 |
UniProt Secondary Accession: | Q9HBX8,Q5T509, Q5T512, Q6UY15, Q86VU0, Q96K69, Q9BYD7 |
UniProt Related Accession: | Q9HBX8 |
Molecular Weight: | 99,295 Da |
NCBI Full Name: | Leucine-rich repeat-containing G-protein coupled receptor 6 |
NCBI Synonym Full Names: | leucine-rich repeat containing G protein-coupled receptor 6 |
NCBI Official Symbol: | LGR6 |
NCBI Official Synonym Symbols: | GPCR; VTS20631 |
NCBI Protein Information: | leucine-rich repeat-containing G-protein coupled receptor 6 |
UniProt Protein Name: | Leucine-rich repeat-containing G-protein coupled receptor 6 |
Protein Family: | Leucine-rich repeat-containing G-protein coupled receptor |
UniProt Gene Name: | LGR6 |
UniProt Entry Name: | LGR6_HUMAN |
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