Anti-IVNS1ABP Antibody (CAB4442)

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SKU:
CAB4442
Product type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
IVNS1ABP
Synonyms:
FLARA3
Synonyms:
HSPC068
Synonyms:
KLHL39
Synonyms:
ND1
Synonyms:
NS-1
Synonyms:
NS1-BP
Synonyms:
NS1BP
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Description

抗体名:IVNS1ABP Rabbit pAb
抗体コード:CAB4442
サイズ:20uL, 50uL, 100uL
同義語:IVNS1ABP, FLARA3, HSPC068, KLHL39, ND1, NS-1, NS1-BP, NS1BP
申し込み:WB, IHC
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IVNS1ABP (NP_006460.2).
申し込み:WB, IHC
推奨される希釈:WB 1:500 - 1:2000 IHC 1:50 - 1:200
反応性:Human, Mouse, Rat
ポジティブサンプル:HT-29, Mouse kidney, Mouse lung, Rat spleen
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IVNS1ABP (NP_006460.2).
精製方法:Affinity purification
保管所:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:MIPN GYLM FEDE NFIE SSVA KLNA LRKS GQFC DVRL QVCG HEML AHRA VLAC CSPY LFEI FNSD SDPH GISH VKFD DLNP EAVE VLLN YAYT AQLK ADKE LVKD VYSA AKKL KMDR VKQV CGDY LLSR MDVT SCIS YRNF ASCM GDSR LLNK VDAY IQEH LLQI SEEE EFLK LPRL KLEV MLED NVCL PSNG KLYT KVIN WVQR SIWE NGDS LEEL MEEV QTLY YSAD HKLL DGNL LDGQ AEVF GSDD DHIQ FVQK KPPR ENGH KQIS SSST GCLS SPNA TVQS PKHE WKIV ASEK TSNN
遺伝子ID:10625
Uniprot:Q9Y6Y0
セルラーロケーション:Cytoplasm, Nucleus, cytoskeleton, nucleoplasm
計算された分子量:71kDa
観察された分子量:72kDa
UniProt Protein Function:IVNS1ABP: Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines. May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 1q25.1-q31.1

Cellular Component: nucleoplasm; spliceosome; transcription factor complex; cytoplasm; actin cytoskeleton

Biological Process: transcription from RNA polymerase III promoter; viral reproduction; response to virus; RNA splicing

UniProt Code:Q9Y6Y0
NCBI GenInfo Identifier:146325015
NCBI Gene ID:10625
NCBI Accession:Q9Y6Y0.3
UniProt Secondary Accession:Q9Y6Y0,Q1G4T6, Q1G4T7, Q5TF75, Q6NW38, Q7LCG2, Q9NZX0 Q9Y480, A8K8R6,
UniProt Related Accession:Q9Y6Y0
Molecular Weight:642
NCBI Full Name:Influenza virus NS1A-binding protein
NCBI Synonym Full Names:influenza virus NS1A binding protein
NCBI Official Symbol:IVNS1ABP  
NCBI Official Synonym Symbols:ND1; NS-1; NS1BP; FLARA3; KLHL39; NS1-BP; HSPC068  
NCBI Protein Information:influenza virus NS1A-binding protein; NS1-binding protein; NCX downstream gene 1; kelch-like family member 39; aryl hydrocarbon receptor-associated 3; aryl hydrocarbon receptor-associated protein 3
UniProt Protein Name:Influenza virus NS1A-binding protein
UniProt Synonym Protein Names:Aryl hydrocarbon receptor-associated protein 3
Protein Family:Influenza virus NS1A-binding protein
UniProt Gene Name:IVNS1ABP  
UniProt Entry Name:NS1BP_HUMAN
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