IVNS1ABP Antibody, HRP conjugated (PACO63532)
- SKU:
- PACO63532
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | IVNS1ABP Antibody, HRP conjugated (PACO63532) |
抗体コード: | PACO63532 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Influenza virus NS1A-binding protein (401-642AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription. |
シノニム: | Influenza virus NS1A-binding protein (NS1-BP) (NS1-binding protein) (Aryl hydrocarbon receptor-associated protein 3), IVNS1ABP, ARA3 FLARA3 KIAA0850 NS1 NS1BP |
UniProt Protein Function: | IVNS1ABP: Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines. May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q25.1-q31.1 Cellular Component: nucleoplasm; spliceosome; transcription factor complex; cytoplasm; actin cytoskeleton Biological Process: transcription from RNA polymerase III promoter; viral reproduction; response to virus; RNA splicing |
UniProt Code: | Q9Y6Y0 |
NCBI GenInfo Identifier: | 146325015 |
NCBI Gene ID: | 10625 |
NCBI Accession: | Q9Y6Y0.3 |
UniProt Secondary Accession: | Q9Y6Y0,Q1G4T6, Q1G4T7, Q5TF75, Q6NW38, Q7LCG2, Q9NZX0 Q9Y480, A8K8R6, |
UniProt Related Accession: | Q9Y6Y0 |
Molecular Weight: | 642 |
NCBI Full Name: | Influenza virus NS1A-binding protein |
NCBI Synonym Full Names: | influenza virus NS1A binding protein |
NCBI Official Symbol: | IVNS1ABP |
NCBI Official Synonym Symbols: | ND1; NS-1; NS1BP; FLARA3; KLHL39; NS1-BP; HSPC068 |
NCBI Protein Information: | influenza virus NS1A-binding protein; NS1-binding protein; NCX downstream gene 1; kelch-like family member 39; aryl hydrocarbon receptor-associated 3; aryl hydrocarbon receptor-associated protein 3 |
UniProt Protein Name: | Influenza virus NS1A-binding protein |
UniProt Synonym Protein Names: | Aryl hydrocarbon receptor-associated protein 3 |
Protein Family: | Influenza virus NS1A-binding protein |
UniProt Gene Name: | IVNS1ABP |
UniProt Entry Name: | NS1BP_HUMAN |