Anti-DLL1 Antibody (CAB5509)
- SKU:
- CAB5509
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Description
抗体名: | Anti-DLL1 Antibody |
抗体コード: | CAB5509 |
抗体サイズ: | 100µL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant protein of human DLL1 |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | Recombinant protein |
免疫原: | Recombinant protein of human DLL1 |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 28514 |
Uniprot: | O00548 |
セルラーロケーション: | Apical cell membrane, Cell junction, Membrane raft, Single-pass type I membrane protein, adherens junction |
計算された分子量: | 27kDa/78kDa |
観察された分子量: | 78kDa |
同義語: | DLL1, DELTA1, DL1, Delta |
バックグラウンド: | DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. |
UniProt Protein Function: | DLL1: Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. Interacts with Notch receptors. Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Membrane protein, integral; Cell development/differentiation Chromosomal Location of Human Ortholog: 6q27 Cellular Component: integral to plasma membrane; plasma membrane; extracellular region; cytoplasmic vesicle Molecular Function:protein binding; calcium ion binding; Notch binding Biological Process: regulation of cell adhesion; Notch signaling pathway; negative regulation of myeloid cell differentiation; negative regulation of interleukin-10 production; Notch receptor processing; cell fate determination; compartment specification; somite specification; cell-cell signaling; negative regulation of auditory receptor cell differentiation; hemopoiesis; positive regulation of transcription from RNA polymerase II promoter; heart looping; determination of left/right symmetry; cell differentiation; inner ear development; positive regulation of Notch signaling pathway |
NCBI Summary: | DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq, Jul 2008] |
UniProt Code: | O00548 |
NCBI GenInfo Identifier: | 118582508 |
NCBI Gene ID: | 28514 |
NCBI Accession: | O00548.2 |
UniProt Secondary Accession: | O00548,Q9NU41, Q9UJV2, B2RAK7, B5M0B3, |
UniProt Related Accession: | O00548 |
Molecular Weight: | 723 |
NCBI Full Name: | Delta-like protein 1 |
NCBI Synonym Full Names: | delta-like 1 (Drosophila) |
NCBI Official Symbol: | DLL1 |
NCBI Official Synonym Symbols: | DL1; Delta; DELTA1 |
NCBI Protein Information: | delta-like protein 1; H-Delta-1; drosophila Delta homolog 1 |
UniProt Protein Name: | Delta-like protein 1 |
UniProt Synonym Protein Names: | Drosophila Delta homolog 1; Delta1; H-Delta-1 |
Protein Family: | Delta-like protein |
UniProt Gene Name: | DLL1 |
UniProt Entry Name: | DLL1_HUMAN |