Anti-APPL1 Antibody (CAB4606)
- SKU:
- CAB4606
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- APPL1
- Synonyms:
- APPL
- Synonyms:
- DIP13alpha
- Synonyms:
- MODY14
Frequently bought together:
Description
| 抗体名: | APPL1 Rabbit pAb |
| 抗体コード: | CAB4606 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | APPL1, APPL, DIP13alpha, MODY14 |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human APPL1 (NP_036228.1). |
| 申し込み: | WB |
| 推奨される希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | SKOV3, SH-SY5Y, 293T, HL-60, Mouse brain, Mouse lung, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human APPL1 (NP_036228.1). |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MPGI DKLP IEET LEDS PQTR SLLG VFEE DATA ISNY MNQL YQAM HRIY DAQN ELSA ATHL TSKL LKEY EKQR FPLG GDDE VMSS TLQQ FSKV IDEL SSCH AVLS TQLA DAMM FPIT QFKE RDLK EILT LKEV FQIA SNDH DAAI NRYS RLSK KREN DKVK YEVT EDVY TSRK KQHQ TMMH YFCA LNTL QYKK KIAL LEPL LGYM QAQI SF |
| 遺伝子ID: | 26060 |
| Uniprot: | Q9UKG1 |
| セルラーロケーション: | Early endosome membrane, Nucleus, Peripheral membrane protein |
| 計算された分子量: | 79kDa |
| 観察された分子量: | 95kDa |
| UniProt Protein Function: | Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway. |
| NCBI Summary: | The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UKG1 |
| NCBI GenInfo Identifier: | 61213025 |
| NCBI Gene ID: | 26060 |
| NCBI Accession: | Q9UKG1.1 |
| UniProt Secondary Accession: | Q9UKG1,Q9P2B9, |
| UniProt Related Accession: | Q9UKG1 |
| Molecular Weight: | 83 kDa |
| NCBI Full Name: | DCC-interacting protein 13-alpha |
| NCBI Synonym Full Names: | adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 |
| NCBI Official Symbol: | APPL1 |
| NCBI Official Synonym Symbols: | APPL; MODY14; DIP13alpha |
| NCBI Protein Information: | DCC-interacting protein 13-alpha |
| UniProt Protein Name: | DCC-interacting protein 13-alpha |
| UniProt Synonym Protein Names: | Adapter protein containing PH domain, PTB domain and leucine zipper motif 1 |
| Protein Family: | DCC-interacting protein |
| UniProt Gene Name: | APPL1 |
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