APPL1 Antibody (PACO42350)
- SKU:
- PACO42350
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | APPL1 Antibody (PACO42350) |
抗体コード: | PACO42350 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human DCC-interacting protein 13-α protein (214-495AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO42350 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human heart tissue using PACO42350 at dilution of 1:100. |
バックグラウンド: | Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. |
シノニム: | DCC-interacting protein 13-α (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1), APPL1, APPL DIP13A KIAA1428 |
UniProt Protein Function: | Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway. |
NCBI Summary: | The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UKG1 |
NCBI GenInfo Identifier: | 61213025 |
NCBI Gene ID: | 26060 |
NCBI Accession: | Q9UKG1.1 |
UniProt Secondary Accession: | Q9UKG1,Q9P2B9, |
UniProt Related Accession: | Q9UKG1 |
Molecular Weight: | 83 kDa |
NCBI Full Name: | DCC-interacting protein 13-alpha |
NCBI Synonym Full Names: | adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 |
NCBI Official Symbol: | APPL1 |
NCBI Official Synonym Symbols: | APPL; MODY14; DIP13alpha |
NCBI Protein Information: | DCC-interacting protein 13-alpha |
UniProt Protein Name: | DCC-interacting protein 13-alpha |
UniProt Synonym Protein Names: | Adapter protein containing PH domain, PTB domain and leucine zipper motif 1 |
Protein Family: | DCC-interacting protein |
UniProt Gene Name: | APPL1 |
Antibodies |
Anti-APPL1 Antibody (CAB4606) |
Anti-APPL Antibody (CAB8932) |
APPL1 Antibody (PACO00410) |
APPL1 Antibody (PACO07799) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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