Anti-APC Antibody (CAB17912)
- SKU:
- CAB17912
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-APC Rabbit Monoclonal Antibody |
抗体コード: | CAB17912 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human APC |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | SW480, Mouse brain, Mouse lung, Rat brain |
免疫原: | A synthesized peptide derived from human APC |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 324 |
Uniprot: | P25054 |
セルラーロケーション: | |
計算された分子量: | 160kDa |
観察された分子量: | 160kDa |
同義語: | APC, BTPS2, DP2, DP2.5, DP3, GS, PPP1R46 |
バックグラウンド: | This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008] |
UniProt Code: | P25054 |
NCBI GenInfo Identifier: | 97535708 |
NCBI Gene ID: | 324 |
NCBI Accession: | P25054.2 |
UniProt Secondary Accession: | P25054,Q15162, Q15163, Q93042, D3DT03, |
UniProt Related Accession: | P25054 |
Molecular Weight: | 461 |
NCBI Full Name: | Adenomatous polyposis coli protein |
NCBI Synonym Full Names: | adenomatous polyposis coli |
NCBI Official Symbol: | APC |
NCBI Official Synonym Symbols: | GS; DP2; DP3; BTPS2; DP2.5; PPP1R46 |
NCBI Protein Information: | adenomatous polyposis coli protein; deleted in polyposis 2.5; adenomatosis polyposis coli tumor suppressor; protein phosphatase 1, regulatory subunit 46 |
UniProt Protein Name: | Adenomatous polyposis coli protein |
UniProt Synonym Protein Names: | Deleted in polyposis 2.5 |
Protein Family: | APC-related protein |
UniProt Gene Name: | APC |
UniProt Entry Name: | APC_HUMAN |