APC Antibody (PACO19119)
- SKU:
- PACO19119
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | APC Antibody (PACO19119) |
抗体コード: | PACO19119 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human APC |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19119(APC Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19119(APC Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. |
シノニム: | adenomatous polyposis coli |
UniProt Code: | P25054 |
NCBI GenInfo Identifier: | 97535708 |
NCBI Gene ID: | 324 |
NCBI Accession: | P25054.2 |
UniProt Secondary Accession: | P25054,Q15162, Q15163, Q93042, D3DT03, |
UniProt Related Accession: | P25054 |
Molecular Weight: | 461 |
NCBI Full Name: | Adenomatous polyposis coli protein |
NCBI Synonym Full Names: | adenomatous polyposis coli |
NCBI Official Symbol: | APC |
NCBI Official Synonym Symbols: | GS; DP2; DP3; BTPS2; DP2.5; PPP1R46 |
NCBI Protein Information: | adenomatous polyposis coli protein; deleted in polyposis 2.5; adenomatosis polyposis coli tumor suppressor; protein phosphatase 1, regulatory subunit 46 |
UniProt Protein Name: | Adenomatous polyposis coli protein |
UniProt Synonym Protein Names: | Deleted in polyposis 2.5 |
Protein Family: | APC-related protein |
UniProt Gene Name: | APC |
UniProt Entry Name: | APC_HUMAN |
Secondary Antibody |
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