ALCAM Antibody (PACO18678)
- SKU:
- PACO18678
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ALCAM Antibody (PACO18678) |
抗体コード: | PACO18678 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, IHC:1:15-1:50 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human ALCAM |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO18678(ALCAM Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18678(ALCAM Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. |
シノニム: | activated leukocyte cell adhesion molecule |
UniProt Protein Function: | ALCAM: Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion Chromosomal Location of Human Ortholog: 3q13.1 Cellular Component: focal adhesion; cell soma; axon; integral to membrane; external side of plasma membrane Molecular Function:protein binding; receptor binding Biological Process: axon guidance; motor axon guidance; signal transduction; cell adhesion |
NCBI Summary: | This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011] |
UniProt Code: | Q13740 |
NCBI GenInfo Identifier: | 118572629 |
NCBI Gene ID: | 214 |
NCBI Accession: | Q13740.2 |
UniProt Secondary Accession: | Q13740,O60892, Q1HGM8, Q1HGM9, Q6PEY4, Q6ZS95, B2RNS3 B4DTU0, |
UniProt Related Accession: | Q13740 |
Molecular Weight: | 33,878 Da |
NCBI Full Name: | CD166 antigen |
NCBI Synonym Full Names: | activated leukocyte cell adhesion molecule |
NCBI Official Symbol: | ALCAM |
NCBI Official Synonym Symbols: | MEMD; CD166 |
NCBI Protein Information: | CD166 antigen |
UniProt Protein Name: | CD166 antigen |
UniProt Synonym Protein Names: | Activated leukocyte cell adhesion molecule; CD_antigen: CD166 |
Protein Family: | CD166 antigen |
UniProt Gene Name: | ALCAM |
UniProt Entry Name: | CD166_HUMAN |
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