VEGFC Antibody, FITC conjugated (PACO32418)
- SKU:
- PACO32418
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Description
抗体名: | VEGFC Antibody, FITC conjugated (PACO32418) |
抗体コード: | PACO32418 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Vascular endothelial growth factor C protein (112-227AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. |
シノニム: | Vascular endothelial growth factor C (VEGF-C) (Flt4 ligand) (Flt4-L) (Vascular endothelial growth factor-related protein) (VRP), VEGFC |
UniProt Protein Function: | VEGFC: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. Homodimer; non-covalent and antiparallel. Spleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte. Belongs to the PDGF/VEGF growth factor family. |
UniProt Protein Details: | Protein type:Cell cycle regulation; Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted; Cytokine Chromosomal Location of Human Ortholog: 4q34.3 Cellular Component: extracellular space; membrane; extracellular region Molecular Function:protein binding; growth factor activity; vascular endothelial growth factor receptor 3 binding; chemoattractant activity Biological Process: signal transduction; induction of positive chemotaxis; negative regulation of cell proliferation; morphogenesis of embryonic epithelium; platelet degranulation; positive chemotaxis; regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of cell proliferation; negative regulation of blood pressure; angiogenesis; positive regulation of cell-matrix adhesion; response to drug; substrate-bound cell migration; positive regulation of neuroblast proliferation; platelet activation; positive regulation of blood vessel endothelial cell migration; positive regulation of protein amino acid autophosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; organ morphogenesis; positive regulation of angiogenesis; positive regulation of protein secretion; positive regulation of cell division; blood coagulation; vascular endothelial growth factor receptor signaling pathway; positive regulation of epithelial cell proliferation Disease: Lymphedema, Hereditary, Id |
NCBI Summary: | The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors. [provided by RefSeq, Apr 2014] |
UniProt Code: | P49767 |
NCBI GenInfo Identifier: | 1718154 |
NCBI Gene ID: | 7424 |
NCBI Accession: | P49767.1 |
UniProt Secondary Accession: | P49767,B2R9Q8, |
UniProt Related Accession: | P49767 |
Molecular Weight: | 46,883 Da |
NCBI Full Name: | Vascular endothelial growth factor C |
NCBI Synonym Full Names: | vascular endothelial growth factor C |
NCBI Official Symbol: | VEGFC |
NCBI Official Synonym Symbols: | VRP; Flt4-L; LMPH1D |
NCBI Protein Information: | vascular endothelial growth factor C; FLT4 ligand DHM; vascular endothelial growth factor-related protein |
UniProt Protein Name: | Vascular endothelial growth factor C |
UniProt Synonym Protein Names: | Flt4 ligand; Flt4-L; Vascular endothelial growth factor-related protein; VRP |
Protein Family: | Vascular endothelial growth factor |
UniProt Gene Name: | VEGFC |
UniProt Entry Name: | VEGFC_HUMAN |