USP47 Antibody, FITC conjugated (PACO40164)
- SKU:
- PACO40164
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | USP47 Antibody, FITC conjugated (PACO40164) |
抗体コード: | PACO40164 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Ubiquitin carboxyl-terminal hydrolase 47 protein (1-157AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase β (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level. |
シノニム: | Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.4.19.12) (Deubiquitinating enzyme 47) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47), USP47 |
UniProt Protein Function: | USP47: Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulates CDC25A expression at a transcriptional level. Belongs to the peptidase C19 family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.4.19.12; Ubiquitin-specific protease; Motility/polarity/chemotaxis; Actin-binding; Protease; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 11p15.3 Cellular Component: cytoplasm; nucleus; SCF ubiquitin ligase complex Molecular Function:protein binding; ubiquitin-specific protease activity Biological Process: base-excision repair; negative regulation of apoptosis; negative regulation of caspase activity; negative regulation of transcription, DNA-dependent; positive regulation of cell growth; response to DNA damage stimulus; response to drug |
UniProt Code: | Q96K76 |
NCBI GenInfo Identifier: | 313104266 |
NCBI Gene ID: | 55031 |
NCBI Accession: | Q96K76.3 |
UniProt Secondary Accession: | Q96K76,Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1, B3KXF5 E9PM46, |
UniProt Related Accession: | Q96K76 |
Molecular Weight: | 154,697 Da |
NCBI Full Name: | Ubiquitin carboxyl-terminal hydrolase 47 |
NCBI Synonym Full Names: | ubiquitin specific peptidase 47 |
NCBI Official Symbol: | USP47 |
NCBI Official Synonym Symbols: | TRFP |
NCBI Protein Information: | ubiquitin carboxyl-terminal hydrolase 47 |
UniProt Protein Name: | Ubiquitin carboxyl-terminal hydrolase 47 |
UniProt Synonym Protein Names: | Deubiquitinating enzyme 47; Ubiquitin thioesterase 47; Ubiquitin-specific-processing protease 47 |
Protein Family: | Ubiquitin carboxyl-terminal hydrolase |
UniProt Gene Name: | USP47 |
UniProt Entry Name: | UBP47_HUMAN |