TSLP Antibody, Biotin conjugated (PACO30841)
- SKU:
- PACO30841
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | TSLP Antibody, Biotin conjugated (PACO30841) |
抗体コード: | PACO30841 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Thymic stromal lymphopoietin protein (29-159AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Isoform 1: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. |
シノニム: | Thymic stromal lymphopoietin, TSLP |
UniProt Protein Function: | TSLP: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 5q22.1 Cellular Component: extracellular space Molecular Function:cytokine activity |
NCBI Summary: | This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012] |
UniProt Code: | Q969D9 |
NCBI GenInfo Identifier: | 74751719 |
NCBI Gene ID: | 85480 |
NCBI Accession: | Q969D9.1 |
UniProt Secondary Accession: | Q969D9,Q8IW99, Q96AU7, G3XAM8, |
UniProt Related Accession: | Q969D9 |
Molecular Weight: | 7,426 Da |
NCBI Full Name: | Thymic stromal lymphopoietin |
NCBI Synonym Full Names: | thymic stromal lymphopoietin |
NCBI Official Symbol: | TSLP |
NCBI Protein Information: | thymic stromal lymphopoietin |
UniProt Protein Name: | Thymic stromal lymphopoietin |
Protein Family: | Thymic stromal lymphopoietin |
UniProt Gene Name: | TSLP |
UniProt Entry Name: | TSLP_HUMAN |