TIAL1 Antibody, Biotin conjugated (PACO63718)
- SKU:
- PACO63718
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | TIAL1 Antibody, Biotin conjugated (PACO63718) |
抗体コード: | PACO63718 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Nucleolysin TIAR protein (9-277AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | RNA-binding protein. Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis. |
シノニム: | Nucleolysin TIAR (TIA-1-related protein), TIAL1 |
UniProt Protein Function: | TIAL1: a member of a family of RNA-binding proteins that possesses nucleolytic activity. A cytotoxic T cell granule-associated protein that has been shown to bind specifically to poly(A) homopolymers and to fragment DNA in permeabilized target cells. Members of this protein family may be involved in the induction of apoptosis. Two splice variant isoforms have been described. |
UniProt Protein Details: | Protein type:RNA-binding; Apoptosis Chromosomal Location of Human Ortholog: 10q Cellular Component: stress granule; lysosome; cytoplasm; nucleus Molecular Function:RNA binding; nucleotide binding; AU-rich element binding Biological Process: regulation of transcription from RNA polymerase II promoter; apoptosis; stem cell division; positive regulation of cell proliferation; defense response; germ cell development |
NCBI Summary: | The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q01085 |
NCBI GenInfo Identifier: | 267131 |
NCBI Gene ID: | 7073 |
NCBI Accession: | Q01085.1 |
UniProt Secondary Accession: | Q01085,P70318, |
UniProt Related Accession: | Q01085 |
Molecular Weight: | 375 |
NCBI Full Name: | Nucleolysin TIAR |
NCBI Synonym Full Names: | TIA1 cytotoxic granule-associated RNA binding protein-like 1 |
NCBI Official Symbol: | TIAL1 |
NCBI Official Synonym Symbols: | TCBP; TIAR |
NCBI Protein Information: | nucleolysin TIAR; T-cluster binding protein; TIA-1-related nucleolysin; aging-associated gene 7 protein |
UniProt Protein Name: | Nucleolysin TIAR |
UniProt Synonym Protein Names: | TIA-1-related protein |
UniProt Gene Name: | TIAL1 |
UniProt Entry Name: | TIAR_HUMAN |