SRGAP1 Antibody, HRP conjugated (PACO50731)
- SKU:
- PACO50731
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | SRGAP1 Antibody, HRP conjugated (PACO50731) |
抗体コード: | PACO50731 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human SLIT-ROBO Rho GTPase-activating protein 1 protein (136-192AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42. |
シノニム: | SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho GTPase-activating protein 13), SRGAP1, ARHGAP13 KIAA1304 |
UniProt Protein Function: | ARHGAP13: GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:GAPs; GAPs, Rac/Rho Chromosomal Location of Human Ortholog: 12q14.2 Cellular Component: cytoplasm; cytosol Molecular Function:GTPase activator activity; protein binding; Rac GTPase binding Biological Process: negative regulation of cell migration; regulation of small GTPase mediated signal transduction Disease: Thyroid Carcinoma, Follicular |
UniProt Code: | Q7Z6B7 |
NCBI GenInfo Identifier: | 48428624 |
NCBI Gene ID: | 57522 |
NCBI Accession: | Q7Z6B7.1 |
UniProt Secondary Accession: | Q7Z6B7,Q9H8A3, Q9P2P2, |
UniProt Related Accession: | Q7Z6B7 |
Molecular Weight: | 121,594 Da |
NCBI Full Name: | SLIT-ROBO Rho GTPase-activating protein 1 |
NCBI Synonym Full Names: | SLIT-ROBO Rho GTPase activating protein 1 |
NCBI Official Symbol: | SRGAP1 |
NCBI Official Synonym Symbols: | NMTC2; ARHGAP13 |
NCBI Protein Information: | SLIT-ROBO Rho GTPase-activating protein 1 |
UniProt Protein Name: | SLIT-ROBO Rho GTPase-activating protein 1 |
UniProt Synonym Protein Names: | Rho GTPase-activating protein 13 |
Protein Family: | SLIT-ROBO Rho GTPase-activating protein |
UniProt Gene Name: | SRGAP1 |
UniProt Entry Name: | SRGP1_HUMAN |