SMPD3 Antibody, FITC conjugated (PACO41476)
- SKU:
- PACO41476
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | SMPD3 Antibody, FITC conjugated (PACO41476) |
抗体コード: | PACO41476 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Sphingomyelin phosphodiesterase 3 protein (401-655AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization. |
シノニム: | Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (nSMase-2) (nSMase2) (Neutral sphingomyelinase II), SMPD3 |
UniProt Protein Function: | SMPD3: Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization. Belongs to the neutral sphingomyelinase family. |
UniProt Protein Details: | Protein type:Lipid Metabolism - sphingolipid; Phospholipase; Membrane protein, integral; EC 3.1.4.12 Chromosomal Location of Human Ortholog: 16q22.1 Cellular Component: plasma membrane Biological Process: glycosphingolipid metabolic process; sphingomyelin catabolic process |
UniProt Code: | Q9NY59 |
NCBI GenInfo Identifier: | 73921262 |
NCBI Gene ID: | 55512 |
NCBI Accession: | Q9NY59.1 |
UniProt Secondary Accession: | Q9NY59,Q2M1S8, B7ZL82, |
UniProt Related Accession: | Q9NY59 |
Molecular Weight: | 70,170 Da |
NCBI Full Name: | Sphingomyelin phosphodiesterase 3 |
NCBI Synonym Full Names: | sphingomyelin phosphodiesterase 3 |
NCBI Official Symbol: | SMPD3 |
NCBI Official Synonym Symbols: | NSMASE2 |
NCBI Protein Information: | sphingomyelin phosphodiesterase 3 |
UniProt Protein Name: | Sphingomyelin phosphodiesterase 3 |
UniProt Synonym Protein Names: | Neutral sphingomyelinase 2; nSMase-2; nSMase2; Neutral sphingomyelinase II |
Protein Family: | Sphingomyelin phosphodiesterase |
UniProt Gene Name: | SMPD3 |
UniProt Entry Name: | NSMA2_HUMAN |