SFRP4 Antibody, FITC conjugated (PACO48464)
- SKU:
- PACO48464
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | SFRP4 Antibody, FITC conjugated (PACO48464) |
抗体コード: | PACO48464 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Secreted frizzled-related protein 4 protein (293-346AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake. |
シノニム: | Secreted frizzled-related protein 4 (sFRP-4) (Frizzled protein, human endometrium) (FrpHE), SFRP4, FRPHE |
UniProt Protein Function: | SFRP4: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake. Belongs to the secreted frizzled-related protein (sFRP) family. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 7p14.1 Cellular Component: cell surface; cytoplasm; extracellular space; integral to membrane; nucleus Molecular Function:G-protein coupled receptor activity; protein binding; Wnt receptor activity; Wnt-protein binding Biological Process: negative regulation of cell proliferation; negative regulation of transcription factor activity; phosphate ion homeostasis; positive regulation of apoptosis; positive regulation of epidermal cell differentiation; positive regulation of receptor internalization |
NCBI Summary: | Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q6FHJ7 |
NCBI GenInfo Identifier: | 61216780 |
NCBI Gene ID: | 6424 |
NCBI Accession: | Q6FHJ7.2 |
UniProt Secondary Accession: | Q6FHJ7,O14877, Q05BG7, Q1ZYW2, Q4G124, Q6FHM0, Q6PD64 B4DYC1, |
UniProt Related Accession: | Q6FHJ7 |
Molecular Weight: | 39,827 Da |
NCBI Full Name: | Secreted frizzled-related protein 4 |
NCBI Synonym Full Names: | secreted frizzled related protein 4 |
NCBI Official Symbol: | SFRP4 |
NCBI Official Synonym Symbols: | PYL; FRP-4; FRPHE; sFRP-4 |
NCBI Protein Information: | secreted frizzled-related protein 4 |
UniProt Protein Name: | Secreted frizzled-related protein 4 |
UniProt Synonym Protein Names: | Frizzled protein, human endometrium; FrpHE |
Protein Family: | Secreted frizzled-related protein |
UniProt Gene Name: | SFRP4 |
UniProt Entry Name: | SFRP4_HUMAN |