RPS6KA5 (Ab-376) Antibody (PACO21539)
- SKU:
- PACO21539
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | RPS6KA5 (Ab-376) Antibody (PACO21539) |
抗体コード: | PACO21539 |
サイズ: | 100ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:1000 |
反応性: | Human, Mouse, Rat |
免疫原: | Peptide sequence around aa.374~378 (G-Y-S-F-V) derived from Human MSK1. |
憲法: | Liquid |
ストレージバッファ: | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
精製方法: | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates |
抗体のクローン性: | Polyclonal |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from HUVEC cells using MSK1(Ab-376) Antibody and the same antibody preincubated with blocking peptide. |
シノニム: | MSPK1; RPS6KA5; |
UniProt Protein Function: | MSK1: an AGC kinase of the RSK family. Has two kinase domains connected by a regulatory linker region. Enzyme activity requires the presence of both kinase domains. Is phosphorylated and activated by Erk as well as p38 MAPK in response to growth factors and cellular stress. |
UniProt Protein Details: | Protein type:EC 2.7.11.1; Protein kinase, AGC; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); AGC group; RSK family; MSK subfamily Chromosomal Location of Human Ortholog: 14q31-q32.1 Cellular Component: cytoplasm; nucleoplasm; nucleus Molecular Function:ATP binding; histone serine kinase activity (H3-S10 specific); magnesium ion binding; protein binding; protein kinase activity; protein serine/threonine kinase activity Biological Process: activation of CREB transcription factor; activation of NF-kappaB transcription factor; axon guidance; epidermal growth factor receptor signaling pathway; histone phosphorylation; inflammatory response; innate immune response; MyD88-dependent toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; negative regulation of cytokine production; negative regulation of transcription, DNA-dependent; nerve growth factor receptor signaling pathway; positive regulation of histone acetylation; positive regulation of histone phosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein amino acid phosphorylation; regulation of transcription, DNA-dependent; stimulatory C-type lectin receptor signaling pathway; stress-activated MAPK cascade; toll-like receptor 10 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 5 signaling pathway; toll-like receptor 9 signaling pathway; toll-like receptor signaling pathway |
UniProt Code: | O75582 |
NCBI GenInfo Identifier: | 37999482 |
NCBI Gene ID: | 9252 |
NCBI Accession: | O75582.1 |
UniProt Secondary Accession: | O75582,O95316, Q96AF7, B7Z2Y5, |
UniProt Related Accession: | O75582 |
Molecular Weight: | 81,780 Da |
NCBI Full Name: | Ribosomal protein S6 kinase alpha-5 |
NCBI Synonym Full Names: | ribosomal protein S6 kinase A5 |
NCBI Official Symbol: | RPS6KA5 |
NCBI Official Synonym Symbols: | MSK1; RLPK; MSPK1 |
NCBI Protein Information: | ribosomal protein S6 kinase alpha-5 |
UniProt Protein Name: | Ribosomal protein S6 kinase alpha-5 |
UniProt Synonym Protein Names: | 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen- and stress-activated protein kinase 1; RSK-like protein kinase; RSKL |
Protein Family: | Ribosomal protein S6 kinase |
UniProt Gene Name: | RPS6KA5 |
UniProt Entry Name: | KS6A5_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |