RFX1 Antibody, Biotin conjugated (PACO57943)
- SKU:
- PACO57943
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | RFX1 Antibody, Biotin conjugated (PACO57943) |
抗体コード: | PACO57943 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human MHC class II regulatory factor RFX1 protein (36-133AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Regulatory factor essential for MHC class II genes expression. Binds to the X boxes of MHC class II genes. Also binds to an inverted repeat (ENH1) required for hepatitis B virus genes expression and to the most upstream element (alpha) of the RPL30 promoter. |
シノニム: | MHC class II regulatory factor RFX1 (Enhancer factor C) (EF-C) (Regulatory factor X 1) (RFX) (Transcription factor RFX1), RFX1 |
UniProt Protein Function: | RFX1: Regulatory factor essential for MHC class II genes expression. Binds to the X boxes of MHC class II genes. Also binds to an inverted repeat (ENH1) required for hepatitis B virus genes expression and to the most upstream element (alpha) of the RPL30 promoter. Belongs to the RFX family. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 19p13.1 Cellular Component: intracellular membrane-bound organelle; nucleoplasm; nucleus Molecular Function:protein binding; RNA polymerase II transcription factor activity, enhancer binding Biological Process: immune response |
NCBI Summary: | This gene encodes a member of the regulatory factor X (RFX) family of transcription factors, which are characterized by a winged-helix DNA-binding domain. The encoded transcription factor contains an N-terminal activation domain and a C-terminal repression domain, and may activate or repress target gene expression depending on cellular context. This transcription factor has been shown to regulate a wide variety of genes involved in immunity and cancer, including the MHC class II genes and genes that may be involved in cancer progression. This gene exhibits altered expression in glioblastoma and the autoimmune disease systemic lupus erythematosis (SLE). [provided by RefSeq, Jul 2016] |
UniProt Code: | P22670 |
NCBI GenInfo Identifier: | 288558824 |
NCBI Gene ID: | 5989 |
NCBI Accession: | P22670.2 |
UniProt Related Accession: | P22670 |
Molecular Weight: | 104,758 Da |
NCBI Full Name: | MHC class II regulatory factor RFX1 |
NCBI Synonym Full Names: | regulatory factor X1 |
NCBI Official Symbol: | RFX1 |
NCBI Official Synonym Symbols: | EFC; RFX |
NCBI Protein Information: | MHC class II regulatory factor RFX1 |
UniProt Protein Name: | MHC class II regulatory factor RFX1 |
UniProt Synonym Protein Names: | Enhancer factor C; EF-C; Regulatory factor X 1; RFX; Transcription factor RFX1 |
Protein Family: | RFX-like DNA-binding protein |
UniProt Gene Name: | RFX1 |
UniProt Entry Name: | RFX1_HUMAN |