RFC4 Antibody, Biotin conjugated (PACO51921)
- SKU:
- PACO51921
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | RFC4 Antibody, Biotin conjugated (PACO51921) |
抗体コード: | PACO51921 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Replication factor C subunit 4 protein (9-142AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template. |
シノニム: | Replication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37), RFC4 |
UniProt Protein Function: | RFC4: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template. Belongs to the activator 1 small subunits family. |
UniProt Protein Details: | Protein type:DNA replication Chromosomal Location of Human Ortholog: 3q27 Cellular Component: nucleoplasm; DNA replication factor C complex; cytoplasm; nucleus Molecular Function:protein binding; ATP binding; DNA clamp loader activity Biological Process: telomere maintenance via semi-conservative replication; nucleotide-excision repair; transcription-coupled nucleotide-excision repair; telomere maintenance via recombination; DNA strand elongation during DNA replication; mitotic cell cycle; nucleotide-excision repair, DNA gap filling; DNA replication; DNA repair; telomere maintenance |
NCBI Summary: | The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008] |
UniProt Code: | P35249 |
NCBI GenInfo Identifier: | 1703052 |
NCBI Gene ID: | 5984 |
NCBI Accession: | P35249.2 |
UniProt Secondary Accession: | P35249,Q6FHX7, B4DM41, D3DNV2, |
UniProt Related Accession: | P35249 |
Molecular Weight: | 363 |
NCBI Full Name: | Replication factor C subunit 4 |
NCBI Synonym Full Names: | replication factor C (activator 1) 4, 37kDa |
NCBI Official Symbol: | RFC4 |
NCBI Official Synonym Symbols: | A1; RFC37 |
NCBI Protein Information: | replication factor C subunit 4; A1 37 kDa subunit; RFC 37 kDa subunit; RF-C 37 kDa subunit; activator 1 subunit 4; activator 1 37 kDa subunit; replication factor C 37 kDa subunit |
UniProt Protein Name: | Replication factor C subunit 4 |
UniProt Synonym Protein Names: | Activator 1 37 kDa subunit; A1 37 kDa subunit; Activator 1 subunit 4; Replication factor C 37 kDa subunit; RF-C 37 kDa subunit; RFC37 |
Protein Family: | Replication factor |
UniProt Gene Name: | RFC4 |
UniProt Entry Name: | RFC4_HUMAN |