PSMD9 Antibody, FITC conjugated (PACO49932)
- SKU:
- PACO49932
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Description
抗体名: | PSMD9 Antibody, FITC conjugated (PACO49932) |
抗体コード: | PACO49932 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human 26S proteasome non-ATPase regulatory subunit 9 protein (103-150AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). During the base subcomplex assembly is part of an intermediate PSMD9:PSMC6:PSMC3 module, also known as modulator trimer complex; PSMD9 is released during the further base assembly process. |
シノニム: | 26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27), PSMD9 |
UniProt Protein Function: | PSMD9: Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). During the base subcomplex assembly is part of an intermediate PSMD9:PSMC6:PSMC3 module, also known as modulator trimer complex; PSMD9 is released during the further base assembly process. Belongs to the proteasome subunit p27 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Protease; Proteasome complex Chromosomal Location of Human Ortholog: 12q24.31-q24.32 Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus Molecular Function:bHLH transcription factor binding; protein binding; transcription coactivator activity Biological Process: anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; MAPKKK cascade; negative regulation of insulin secretion; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; positive regulation of insulin secretion; positive regulation of transcription, DNA-dependent; positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; regulation of amino acid metabolic process; regulation of mRNA stability; stimulatory C-type lectin receptor signaling pathway; T cell receptor signaling pathway; tumor necrosis factor-mediated signaling pathway; Wnt receptor signaling pathway, planar cell polarity pathway |
NCBI Summary: | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, May 2012] |
UniProt Code: | O00233 |
NCBI GenInfo Identifier: | 317373521 |
NCBI Gene ID: | 5715 |
NCBI Accession: | O00233.3 |
UniProt Secondary Accession: | O00233,Q9BQ42, B2RD35, G3V1Q6, |
UniProt Related Accession: | O00233 |
Molecular Weight: | 13,053 Da |
NCBI Full Name: | 26S proteasome non-ATPase regulatory subunit 9 |
NCBI Synonym Full Names: | proteasome 26S subunit, non-ATPase 9 |
NCBI Official Symbol: | PSMD9 |
NCBI Official Synonym Symbols: | p27; Rpn4 |
NCBI Protein Information: | 26S proteasome non-ATPase regulatory subunit 9 |
UniProt Protein Name: | 26S proteasome non-ATPase regulatory subunit 9 |
UniProt Synonym Protein Names: | 26S proteasome regulatory subunit p27 |
Protein Family: | 26S proteasome non-ATPase regulatory |
UniProt Gene Name: | PSMD9 |
UniProt Entry Name: | PSMD9_HUMAN |