PNOC Antibody (PACO18761)
- SKU:
- PACO18761
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PNOC Antibody (PACO18761) |
抗体コード: | PACO18761 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human PONC |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane: Human liver cancer tissue, Primary antibody: PACO18761(PONC Antibody) at dilution 1/1200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second. |
バックグラウンド: | Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development |
シノニム: | prepronociceptin |
UniProt Protein Function: | PNOC: Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development. Belongs to the opioid neuropeptide precursor family. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 8p21 Cellular Component: extracellular region Molecular Function:neuropeptide hormone activity; protein binding; opioid peptide activity Biological Process: synaptic transmission; neuropeptide signaling pathway; sensory perception; signal transduction |
NCBI Summary: | This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include nociceptin, nocistatin, and orphanin FQ2 (OFQ2). Nociceptin, also known as orphanin FQ, is a 17-amino acid neuropeptide that binds to the nociceptin receptor to induce increased pain sensitivity, and may additionally regulate body temperature, learning and memory, and hunger. Another product of the encoded preproprotein, nocistatin, may inhibit the effects of nociceptin. [provided by RefSeq, Jul 2015] |
UniProt Code: | Q13519 |
NCBI GenInfo Identifier: | 2494348 |
NCBI Gene ID: | 5368 |
NCBI Accession: | Q13519.1 |
UniProt Related Accession: | Q13519 |
Molecular Weight: | 13kDa; 20kDa |
NCBI Full Name: | Prepronociceptin |
NCBI Synonym Full Names: | prepronociceptin |
NCBI Official Symbol: | PNOC |
NCBI Official Synonym Symbols: | NOP; OFQ; N/OFQ; PPNOC; ppN/OFQ |
NCBI Protein Information: | prepronociceptin |
UniProt Protein Name: | Prepronociceptin |
UniProt Synonym Protein Names: | Orphanin FQ; PPNOC |
Protein Family: | Prepronociceptin |
UniProt Gene Name: | PNOC |
UniProt Entry Name: | PNOC_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |