PFDN5 Antibody, Biotin conjugated (PACO28269)
- SKU:
- PACO28269
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
| 抗体名: | PFDN5 Antibody, Biotin conjugated (PACO28269) |
| 抗体コード: | PACO28269 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Prefoldin subunit 5 protein (2-154AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Biotin |
| バックグラウンド: | Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. |
| シノニム: | Prefoldin subunit 5 (Myc modulator 1) (c-Myc-binding protein Mm-1), PFDN5, MM1 PFD5 |
| UniProt Protein Function: | PFDN5: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC. Belongs to the prefoldin subunit alpha family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 12q12 Cellular Component: cytoplasm; nucleus; prefoldin complex Molecular Function:protein binding; unfolded protein binding; transcription corepressor activity Biological Process: 'de novo' posttranslational protein folding; cellular protein metabolic process; regulation of transcription, DNA-dependent; protein folding; retina development in camera-type eye; negative regulation of transcription, DNA-dependent |
| NCBI Summary: | This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q99471 |
| NCBI GenInfo Identifier: | 12231038 |
| NCBI Gene ID: | 5204 |
| NCBI Accession: | Q99471.2 |
| UniProt Related Accession: | Q99471 |
| Molecular Weight: | 17kDa |
| NCBI Full Name: | Prefoldin subunit 5 |
| NCBI Synonym Full Names: | prefoldin subunit 5 |
| NCBI Official Symbol: | PFDN5 |
| NCBI Official Synonym Symbols: | MM1; MM-1; PFD5 |
| NCBI Protein Information: | prefoldin subunit 5 |
| UniProt Protein Name: | Prefoldin subunit 5 |
| UniProt Synonym Protein Names: | C-Myc-binding protein Mm-1; Myc modulator 1 |
| Protein Family: | Prefoldin |
| UniProt Gene Name: | PFDN5 |
| UniProt Entry Name: | PFD5_HUMAN |
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