NFAM1 Antibody, FITC conjugated (PACO39704)
- SKU:
- PACO39704
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | NFAM1 Antibody, FITC conjugated (PACO39704) |
抗体コード: | PACO39704 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human NFAT activation molecule 1 protein (186-270AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-α promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking. |
シノニム: | NFAT activation molecule 1 (Calcineurin/NFAT-activating ITAM-containing protein) (NFAT-activating protein with ITAM motif 1), NFAM1, CNAIP |
UniProt Protein Function: | NFAM1: May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross- linking. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 22q13.2 Cellular Component: cell surface; integral to membrane; intracellular; lipid raft; plasma membrane Molecular Function:transmembrane receptor activity Biological Process: B cell differentiation; B cell receptor signaling pathway; inflammatory response; positive regulation of B cell receptor signaling pathway; positive regulation of cytokine production; positive regulation of transcription factor activity; regulation of B cell differentiation; signal transduction |
NCBI Summary: | The protein encoded by this gene is a type I membrane receptor that activates cytokine gene promoters such as the IL-13 and TNF-alpha promoters. The encoded protein contains an immunoreceptor tyrosine-based activation motif (ITAM) and is thought to regulate the signaling and development of B-cells. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8NET5 |
NCBI GenInfo Identifier: | 22095335 |
NCBI Gene ID: | 150372 |
NCBI Accession: | NP_666017.1 |
UniProt Secondary Accession: | Q8NET5,Q20WL2, Q5JZ96, Q8IUY8, Q8TEM8, B0QYD0, |
UniProt Related Accession: | Q8NET5 |
Molecular Weight: | 29,686 Da |
NCBI Full Name: | NFAT activation molecule 1 isoform 1 |
NCBI Synonym Full Names: | NFAT activating protein with ITAM motif 1 |
NCBI Official Symbol: | NFAM1 |
NCBI Official Synonym Symbols: | CNAIP |
NCBI Protein Information: | NFAT activation molecule 1 |
UniProt Protein Name: | NFAT activation molecule 1 |
UniProt Synonym Protein Names: | Calcineurin/NFAT-activating ITAM-containing protein; NFAT-activating protein with ITAM motif 1 |
Protein Family: | NFAT activation molecule |
UniProt Gene Name: | NFAM1 |
UniProt Entry Name: | NFAM1_HUMAN |