MLLT10 Antibody, FITC conjugated (PACO28284)
- SKU:
- PACO28284
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | MLLT10 Antibody, FITC conjugated (PACO28284) |
抗体コード: | PACO28284 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Protein AF-10 protein (1-126AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. |
シノニム: | Protein AF-10 (ALL1-fused gene from chromosome 10 protein), MLLT10, AF10 |
UniProt Protein Function: | MLLT10: Probably involved in transcriptional regulation. In vitro or as fusion protein with MLL has transactivation activity. Binds to cruciform DNA. A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with MLL/HRX. The result is a rogue activator protein. A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Oncoprotein; Transcription factor Chromosomal Location of Human Ortholog: 10p12 Cellular Component: cytoplasm; nucleoplasm Molecular Function:protein binding Biological Process: positive regulation of transcription from RNA polymerase II promoter Disease: Leukemia, Acute Myeloid |
NCBI Summary: | This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010] |
UniProt Code: | P55197 |
NCBI GenInfo Identifier: | 527504034 |
NCBI Gene ID: | 8028 |
NCBI Accession: | P55197.2 |
UniProt Secondary Accession: | P55197,Q5JT37, Q5VX90, Q66K63, B1ANA8, |
UniProt Related Accession: | P55197 |
Molecular Weight: | 20,047 Da |
NCBI Full Name: | Protein AF-10 |
NCBI Synonym Full Names: | myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 |
NCBI Official Symbol: | MLLT10 |
NCBI Official Synonym Symbols: | AF10 |
NCBI Protein Information: | protein AF-10 |
UniProt Protein Name: | Protein AF-10 |
UniProt Synonym Protein Names: | ALL1-fused gene from chromosome 10 protein |
Protein Family: | Protein |
UniProt Gene Name: | MLLT10 |
UniProt Entry Name: | AF10_HUMAN |