MAP1LC3B Antibody, Biotin conjugated (PACO52861)
- SKU:
- PACO52861
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | MAP1LC3B Antibody, Biotin conjugated (PACO52861) |
抗体コード: | PACO52861 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Microtubule-associated proteins 1A/1B light chain 3B protein (2-100AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway. |
シノニム: | Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta), MAP1LC3B, MAP1ALC3 |
NCBI Summary: | The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9GZQ8 |
NCBI GenInfo Identifier: | 17433141 |
NCBI Gene ID: | 81631 |
NCBI Accession: | Q9GZQ8.3 |
UniProt Related Accession: | Q9GZQ8 |
Molecular Weight: | |
NCBI Full Name: | Microtubule-associated proteins 1A/1B light chain 3B |
NCBI Synonym Full Names: | microtubule associated protein 1 light chain 3 beta |
NCBI Official Symbol: | MAP1LC3B |
NCBI Official Synonym Symbols: | LC3B; ATG8F; MAP1LC3B-a; MAP1A/1BLC3 |
NCBI Protein Information: | microtubule-associated proteins 1A/1B light chain 3B |
UniProt Protein Name: | Microtubule-associated proteins 1A/1B light chain 3B |
UniProt Synonym Protein Names: | Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; MAP1 light chain 3-like protein 2; MAP1A/MAP1B light chain 3 B; MAP1A/MAP1B LC3 B; Microtubule-associated protein 1 light chain 3 beta |
UniProt Gene Name: | MAP1LC3B |
UniProt Entry Name: | MLP3B_HUMAN |