KLF2 Antibody, Biotin conjugated (PACO51229)
- SKU:
- PACO51229
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | KLF2 Antibody, Biotin conjugated (PACO51229) |
抗体コード: | PACO51229 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Krueppel-like factor 2 protein (1-355AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Transcription factor that binds to the CACCC box in the promoter of target genes such as HBB/β globin or NOV and activates their transcription. |
シノニム: | Krueppel-like factor 2 (Lung krueppel-like factor), KLF2, LKLF |
UniProt Protein Function: | KLF2: Binds to the CACCC box in the beta-globin gene promoter and activates transcription. Belongs to the krueppel C2H2-type zinc-finger protein family. |
UniProt Protein Details: | Protein type:C2H2-type zinc finger protein; DNA-binding Chromosomal Location of Human Ortholog: 19p13.11 Molecular Function:protein binding; transcription factor activity Biological Process: positive regulation of nitric oxide biosynthetic process; positive regulation of protein metabolic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent |
NCBI Summary: | Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011] |
UniProt Code: | Q9Y5W3 |
NCBI GenInfo Identifier: | 20141620 |
NCBI Gene ID: | 10365 |
NCBI Accession: | Q9Y5W3.2 |
UniProt Secondary Accession: | Q9Y5W3,Q6IPC4, Q9UJS5, Q9UKR6, |
UniProt Related Accession: | Q9Y5W3 |
Molecular Weight: | 37,420 Da |
NCBI Full Name: | Krueppel-like factor 2 |
NCBI Synonym Full Names: | Kruppel like factor 2 |
NCBI Official Symbol: | KLF2 |
NCBI Official Synonym Symbols: | LKLF |
NCBI Protein Information: | Krueppel-like factor 2 |
UniProt Protein Name: | Krueppel-like factor 2 |
UniProt Synonym Protein Names: | Lung krueppel-like factor |
Protein Family: | Krueppel-like factor |
UniProt Gene Name: | KLF2 |
UniProt Entry Name: | KLF2_HUMAN |