IZUMO1 Antibody, FITC conjugated (PACO37756)
- SKU:
- PACO37756
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | IZUMO1 Antibody, FITC conjugated (PACO37756) |
抗体コード: | PACO37756 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Izumo sperm-egg fusion protein 1 protein (22-292AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. |
シノニム: | Izumo sperm-egg fusion protein 1 (Oocyte binding/fusion factor) (OBF) (Sperm-specific protein izumo), IZUMO1 |
UniProt Protein Function: | IZUMO1: Involved in the fertilization process. May be involved in the fusion of the sperm with the egg. Belongs to the Izumo family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.33 Cellular Component: integral to membrane; plasma membrane Molecular Function:protein homodimerization activity; receptor binding Biological Process: cell adhesion; fusion of sperm to egg plasma membrane; single fertilization; sperm-egg recognition |
NCBI Summary: | The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma membrane binding and fusion (Inoue et al., 2005 [PubMed 15759005]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q8IYV9 |
NCBI GenInfo Identifier: | 296434545 |
NCBI Gene ID: | 284359 |
NCBI Accession: | Q8IYV9.2 |
UniProt Secondary Accession: | Q8IYV9,Q6Q8P6, Q6Q8P7, |
UniProt Related Accession: | Q8IYV9 |
Molecular Weight: | 7,339 Da |
NCBI Full Name: | Izumo sperm-egg fusion protein 1 |
NCBI Synonym Full Names: | izumo sperm-egg fusion 1 |
NCBI Official Symbol: | IZUMO1 |
NCBI Official Synonym Symbols: | OBF; IZUMO |
NCBI Protein Information: | izumo sperm-egg fusion protein 1 |
UniProt Protein Name: | Izumo sperm-egg fusion protein 1 |
UniProt Synonym Protein Names: | Oocyte binding/fusion factor; OBF; Sperm-specific protein izumo |
Protein Family: | Izumo sperm-egg fusion protein |
UniProt Gene Name: | IZUMO1 |
UniProt Entry Name: | IZUM1_HUMAN |