IST1 Antibody (PACO13548)
- SKU:
- PACO13548
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | IST1 Antibody (PACO13548) |
抗体コード: | PACO13548 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | |
反応性: | Human |
免疫原: | Human OLC1 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | KIAA0174;KIAA0174;IST1;MGC117220 ;OLC1 |
UniProt Protein Function: | IST1: Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. Belongs to the IST1 family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Vesicle; Cell cycle regulation Chromosomal Location of Human Ortholog: 16q22.2 Cellular Component: centrosome; cytoplasmic membrane-bound vesicle; ER-Golgi intermediate compartment; midbody; cytosol Molecular Function:protein domain specific binding; protein binding; protein complex binding Biological Process: release of virus from host; protein localization; establishment of protein localization; cell division; positive regulation of proteolysis; abscission; cytokinesis; viral capsid re-envelopment; positive regulation of collateral sprouting |
NCBI Summary: | This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012] |
UniProt Code: | P53990 |
NCBI GenInfo Identifier: | 41281489 |
NCBI Gene ID: | 9798 |
NCBI Accession: | NP_055576.2 |
UniProt Related Accession: | P53990 |
Molecular Weight: | 23kDa; 36kDa; 39kDa; 41kDa |
NCBI Full Name: | IST1 homolog isoform b |
NCBI Synonym Full Names: | IST1 factor associated with ESCRT-III |
NCBI Official Symbol: | IST1 |
NCBI Official Synonym Symbols: | OLC1; CHMP8 |
NCBI Protein Information: | IST1 homolog |
UniProt Protein Name: | IST1 homolog |
UniProt Synonym Protein Names: | Putative MAPK-activating protein PM28 |
Protein Family: | IST1 |
UniProt Gene Name: | IST1 |
UniProt Entry Name: | IST1_HUMAN |