GSDMD Antibody, FITC conjugated (PACO27207)
- SKU:
- PACO27207
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Description
抗体名: | GSDMD Antibody, FITC conjugated (PACO27207) |
抗体コード: | PACO27207 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Gasdermin-D protein (1-256AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | nucleoplasm |
シノニム: | Gasdermin-D (Gasdermin domain-containing protein 1) [Cleaved into: Gasdermin-D, N-terminal (GSDMD-NT); Gasdermin-D, C-terminal (GSDMD-CT)], GSDMD, DFNA5L GSDMDC1 |
UniProt Protein Function: | FKSG10: Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009] |
UniProt Protein Details: | Protein type:Lipid-binding Chromosomal Location of Human Ortholog: 8q24.3 Cellular Component: cytosol; extracellular region; extracellular space; ficolin-1-rich granule lumen; NLRP3 inflammasome complex; nucleoplasm; plasma membrane; tertiary granule lumen Molecular Function:cardiolipin binding; phosphatidic acid binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-4-phosphate binding; phosphatidylserine binding; protein binding Biological Process: cellular response to extracellular stimulus; cytolysis; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; inflammatory response; innate immune response; neutrophil degranulation; pore complex assembly; positive regulation of interleukin-1 beta secretion; protein homooligomerization; pyroptosis |
NCBI Summary: | Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009] |
UniProt Code: | P57764 |
NCBI GenInfo Identifier: | 261878494 |
NCBI Gene ID: | 79792 |
NCBI Accession: | NP_001159709.1 |
UniProt Secondary Accession: | P57764,Q96Q98, A8K702, D3DWJ9, |
UniProt Related Accession: | P57764 |
Molecular Weight: | 52,801 Da |
NCBI Full Name: | gasdermin-D |
NCBI Synonym Full Names: | gasdermin D |
NCBI Official Symbol: | GSDMD |
NCBI Official Synonym Symbols: | DF5L; DFNA5L; FKSG10; GSDMDC1 |
NCBI Protein Information: | gasdermin-D |
UniProt Protein Name: | Gasdermin-D |
UniProt Synonym Protein Names: | Gasdermin domain-containing protein 1 |
Protein Family: | Gasdermin |
UniProt Gene Name: | GSDMD |