GRP Antibody, Biotin conjugated (PACO27200)
- SKU:
- PACO27200
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | GRP Antibody, Biotin conjugated (PACO27200) |
抗体コード: | PACO27200 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Gastrin-releasing peptide protein (31-98AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent memory for fear |
シノニム: | Gastrin-releasing peptide (GRP) [Cleaved into: Neuromedin-C (GRP-10)], GRP |
UniProt Protein Function: | GRP: GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP- receptor gene expression, long-term potentiation, and amygdala- dependent memory for fear. Belongs to the bombesin/neuromedin-B/ranatensin family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 18q21.1-q21.32 Cellular Component: extracellular space; extracellular region Molecular Function:neuropeptide hormone activity; receptor binding Biological Process: neuropeptide signaling pathway; signal transduction |
NCBI Summary: | This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
UniProt Code: | P07492 |
NCBI GenInfo Identifier: | 308153451 |
NCBI Gene ID: | 2922 |
NCBI Accession: | P07492.2 |
UniProt Secondary Accession: | P07492,P07491, P81553, Q14454, Q53YA0, Q9BSY7, |
UniProt Related Accession: | P07492 |
Molecular Weight: | 148 |
NCBI Full Name: | Gastrin-releasing peptide |
NCBI Synonym Full Names: | gastrin-releasing peptide |
NCBI Official Symbol: | GRP |
NCBI Official Synonym Symbols: | BN; GRP-10; proGRP; preproGRP |
NCBI Protein Information: | gastrin-releasing peptide; bombesin; prepro-GRP; neuromedin C; pre-progastrin releasing peptide |
UniProt Protein Name: | Gastrin-releasing peptide |
UniProt Synonym Protein Names: | GRP-10 |
Protein Family: | GrpE protein |
UniProt Gene Name: | GRP |
UniProt Entry Name: | GRP_HUMAN |