GPAM Antibody, Biotin conjugated (PACO52805)
- SKU:
- PACO52805
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Description
抗体名: | GPAM Antibody, Biotin conjugated (PACO52805) |
抗体コード: | PACO52805 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Glycerol-3-phosphate acyltransferase 1, mitochondrial protein (281-459AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. |
シノニム: | Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAT-1) (EC 2.3.1.15), GPAM, GPAT1 KIAA1560 |
UniProt Protein Function: | GPAM: glycerol-3-phosphate acyltransferase is an integral multi-pass enzyme of the mitochondrial outer membrane. It performs the first step in de novo phospholipid biosynthesis. Member of the phospholipid and glycerol acyltransferase family |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Lipid Metabolism - glycerolipid; Mitochondrial; Lipid Metabolism - glycerophospholipid; Membrane protein, integral; Transferase; EC 2.3.1.15 Chromosomal Location of Human Ortholog: 10q25.2 Cellular Component: mitochondrial outer membrane; mitochondrial inner membrane; plasma membrane; integral to membrane Molecular Function:glycerol-3-phosphate O-acyltransferase activity Biological Process: regulation of cytokine secretion; acyl-CoA metabolic process; glycerophospholipid biosynthetic process; triacylglycerol biosynthetic process; positive regulation of multicellular organism growth; cellular lipid metabolic process; fatty acid metabolic process; positive regulation of activated T cell proliferation; fatty acid homeostasis; phospholipid metabolic process; response to glucose stimulus; phosphatidic acid biosynthetic process; CDP-diacylglycerol biosynthetic process; defense response to virus; phospholipid homeostasis |
NCBI Summary: | This gene encodes a mitochondrial enzyme which prefers saturated fatty acids as its substrate for the synthesis of glycerolipids. This metabolic pathway's first step is catalyzed by the encoded enzyme. Two forms for this enzyme exist, one in the mitochondria and one in the endoplasmic reticulum. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011] |
UniProt Code: | Q9HCL2 |
NCBI GenInfo Identifier: | 59803040 |
NCBI Gene ID: | 57678 |
NCBI Accession: | Q9HCL2.3 |
UniProt Secondary Accession: | Q9HCL2,Q5VW51, Q86TA3, |
UniProt Related Accession: | Q9HCL2 |
Molecular Weight: | 828 |
NCBI Full Name: | Glycerol-3-phosphate acyltransferase 1, mitochondrial |
NCBI Synonym Full Names: | glycerol-3-phosphate acyltransferase, mitochondrial |
NCBI Official Symbol: | GPAM |
NCBI Official Synonym Symbols: | GPAT; GPAT1 |
NCBI Protein Information: | glycerol-3-phosphate acyltransferase 1, mitochondrial; GPAT-1; glycerol 3-phosphate acyltransferase, mitochondrial |
UniProt Protein Name: | Glycerol-3-phosphate acyltransferase 1, mitochondrial |
UniProt Gene Name: | GPAM |
UniProt Entry Name: | GPAT1_HUMAN |