GDI1 Antibody (PACO13781)
- SKU:
- PACO13781
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | GDI1 Antibody (PACO13781) |
抗体コード: | PACO13781 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:500-1:1000, WB:1:200-1:1000, IHC:1:25-1:50 |
反応性: | Human, Mouse, Rat |
免疫原: | Fusion protein of human GDI1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO13781(GDI1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: PACO13781(GDI1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO13781(GDI1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. [provided by RefSeq, Jul 2008] |
シノニム: | GDP dissociation inhibitor 1 |
UniProt Protein Function: | GDI1: a GDP dissociation inhibitor protein expressed primarily in neural and sensory tissues. GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the Rab family, small GTP-binding proteins of the Ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from Rab proteins and release GDP from membrane-bound Rabs. Mutations have been linked to X-linked nonspecific mental retardation. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; G protein regulator, misc. Chromosomal Location of Human Ortholog: Xq28 Cellular Component: Golgi apparatus; neuron projection; protein complex; cytoplasm; midbody; cytosol Molecular Function:protein binding; GDP-dissociation inhibitor activity; Rab GDP-dissociation inhibitor activity; GTPase activator activity; Rab GTPase binding Biological Process: protein transport; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; negative regulation of axonogenesis; signal transduction; Rab protein signal transduction; response to calcium ion; positive regulation of GTPase activity Disease: Mental Retardation, X-linked 41 |
NCBI Summary: | GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. [provided by RefSeq, Jul 2008] |
UniProt Code: | P31150 |
NCBI GenInfo Identifier: | 1707886 |
NCBI Gene ID: | 2664 |
NCBI Accession: | P31150.2 |
UniProt Secondary Accession: | P31150,P50394, Q6FG50, Q7Z2G6, Q7Z2G9, Q7Z2H5, Q7Z2I6 |
UniProt Related Accession: | P31150 |
Molecular Weight: | 447 |
NCBI Full Name: | Rab GDP dissociation inhibitor alpha |
NCBI Synonym Full Names: | GDP dissociation inhibitor 1 |
NCBI Official Symbol: | GDI1 |
NCBI Official Synonym Symbols: | 1A; GDIL; MRX41; MRX48; OPHN2; XAP-4; RABGD1A; RABGDIA |
NCBI Protein Information: | rab GDP dissociation inhibitor alpha; GDI-1; protein XAP-4; rab GDI alpha; oligophrenin-2; mental retardation, X-linked 48; rab GDP-dissociation inhibitor, alpha; guanosine diphosphate dissociation inhibitor 1 |
UniProt Protein Name: | Rab GDP dissociation inhibitor alpha |
UniProt Synonym Protein Names: | Guanosine diphosphate dissociation inhibitor 1; GDI-1; Oligophrenin-2; Protein XAP-4 |
Protein Family: | Guanosine nucleotide diphosphate dissociation inhibitor |
UniProt Gene Name: | GDI1 |
UniProt Entry Name: | GDIA_HUMAN |
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