GCLM Antibody (PACO09434)
- SKU:
- PACO09434
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | GCLM Antibody (PACO09434) |
抗体コード: | PACO09434 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human GCLM |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | glutamate-cysteine ligase, modifier subunit;GCLM;GLCLR ; |
UniProt Protein Function: | GCLM: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:Other Amino Acids Metabolism - glutathione Chromosomal Location of Human Ortholog: 1p22.1 Cellular Component: cytosol; glutamate-cysteine ligase complex Molecular Function:enzyme regulator activity; glutamate-cysteine ligase activity; glutamate-cysteine ligase catalytic subunit binding Biological Process: glutamate metabolic process; glutathione biosynthetic process; positive regulation of glutamate-cysteine ligase activity; regulation of blood vessel size; response to drug; response to oxidative stress; sulfur amino acid metabolic process Disease: Myocardial Infarction, Susceptibility To |
NCBI Summary: | Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015] |
UniProt Code: | P48507 |
NCBI GenInfo Identifier: | 1346188 |
NCBI Gene ID: | 2730 |
NCBI Accession: | P48507.1 |
UniProt Secondary Accession: | P48507,Q6FHC1, Q9NPX9, Q9NU74, A8K334, D3DT45, M5A959 |
UniProt Related Accession: | P48507 |
Molecular Weight: | 28,135 Da |
NCBI Full Name: | Glutamate--cysteine ligase regulatory subunit |
NCBI Synonym Full Names: | glutamate-cysteine ligase modifier subunit |
NCBI Official Symbol: | GCLM |
NCBI Official Synonym Symbols: | GLCLR |
NCBI Protein Information: | glutamate--cysteine ligase regulatory subunit |
UniProt Protein Name: | Glutamate--cysteine ligase regulatory subunit |
UniProt Synonym Protein Names: | GCS light chain; Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; Glutamate--cysteine ligase modifier subunit |
Protein Family: | Glutamate--cysteine ligase regulatory |
UniProt Gene Name: | GCLM |
UniProt Entry Name: | GSH0_HUMAN |