FDXR Antibody, FITC conjugated (PACO26723)
- SKU:
- PACO26723
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | FDXR Antibody, FITC conjugated (PACO26723) |
抗体コード: | PACO26723 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human NADPH:adrenodoxin oxidoreductase, mitochondrial protein (33-451AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-β hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. |
シノニム: | NADPH:adrenodoxin oxidoreductase, mitochondrial (AR) (Adrenodoxin reductase) (EC 1.18.1.6) (Ferredoxin--NADP(+) reductase) (Ferredoxin reductase), FDXR, ADXR |
UniProt Protein Function: | FDXR: Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. Belongs to the ferredoxin--NADP reductase type 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Oxidoreductase; Mitochondrial; EC 1.18.1.6 Chromosomal Location of Human Ortholog: 17q25.1 Cellular Component: mitochondrion; mitochondrial matrix Molecular Function:protein binding; ferredoxin-NADP+ reductase activity; NADPH-adrenodoxin reductase activity Biological Process: steroid metabolic process; cholesterol metabolic process; ubiquinone biosynthetic process; generation of precursor metabolites and energy; xenobiotic metabolic process; C21-steroid hormone biosynthetic process; steroid biosynthetic process; sterol metabolic process |
NCBI Summary: | This gene encodes a mitochondrial flavoprotein that initiates electron transport for cytochromes P450 receiving electrons from NADPH. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012] |
UniProt Code: | P22570 |
NCBI GenInfo Identifier: | 85681283 |
NCBI Gene ID: | 2232 |
NCBI Accession: | P22570.3 |
UniProt Related Accession: | P22570 |
Molecular Weight: | Observed Molecular Weight: (Observed)53kD.Predicted Molecular Weight: (Calculated)54kDa. |
NCBI Full Name: | NADPH:adrenodoxin oxidoreductase, mitochondrial |
NCBI Synonym Full Names: | ferredoxin reductase |
NCBI Official Symbol: | FDXR |
NCBI Official Synonym Symbols: | ADR; ADXR; ANOA |
NCBI Protein Information: | NADPH:adrenodoxin oxidoreductase, mitochondrial |
UniProt Protein Name: | NADPH:adrenodoxin oxidoreductase, mitochondrial |
UniProt Synonym Protein Names: | Ferredoxin--NADP(+) reductase; Ferredoxin reductase |
UniProt Gene Name: | FDXR |
UniProt Entry Name: | ADRO_HUMAN |