FDFT1 Antibody, Biotin conjugated (PACO26720)
- SKU:
- PACO26720
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | FDFT1 Antibody, Biotin conjugated (PACO26720) |
抗体コード: | PACO26720 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Squalene synthase protein (2-417AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | endoplasmic reticulum, endoplasmic reticulum membrane, integral component of membrane, farnesyl-diphosphate farnesyltransferase activity, cellular lipid metabolic process, cholesterol biosynthetic process, small molecule metabolic process, steroid biosynthetic process |
シノニム: | Squalene synthase (SQS) (SS) (EC 2.5.1.21) (FPP:FPP farnesyltransferase) (Farnesyl-diphosphate farnesyltransferase), FDFT1 |
UniProt Protein Function: | FDFT1: a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:Oxidoreductase; EC 2.5.1.21; Endoplasmic reticulum; Lipid Metabolism - steroid biosynthesis; Membrane protein, integral; Transferase; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 8p23.1-p22 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane Molecular Function:farnesyl-diphosphate farnesyltransferase activity Biological Process: cholesterol biosynthetic process; steroid biosynthetic process |
NCBI Summary: | This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P37268 |
NCBI GenInfo Identifier: | 585126 |
NCBI Gene ID: | 2222 |
NCBI Accession: | P37268.1 |
UniProt Secondary Accession: | P37268,Q96GT0, B3KQ95, B4DJE5, B4DT56, B7Z1J3, |
UniProt Related Accession: | P37268 |
Molecular Weight: | 43,060 Da |
NCBI Full Name: | Squalene synthase |
NCBI Synonym Full Names: | farnesyl-diphosphate farnesyltransferase 1 |
NCBI Official Symbol: | FDFT1 |
NCBI Official Synonym Symbols: | SS; SQS; DGPT; ERG9 |
NCBI Protein Information: | squalene synthase |
UniProt Protein Name: | Squalene synthase |
UniProt Synonym Protein Names: | FPP:FPP farnesyltransferase; Farnesyl-diphosphate farnesyltransferase |
UniProt Gene Name: | FDFT1 |
UniProt Entry Name: | FDFT_HUMAN |