ERBB4 Antibody (PACO14242)
- SKU:
- PACO14242
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ERBB4 Antibody (PACO14242) |
抗体コード: | PACO14242 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Fusion protein of human ERBB4 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO14242(ERBB4 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO14242(ERBB4 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. |
シノニム: | erb-b2 receptor tyrosine kinase 4 |
NCBI Summary: | This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q15303 |
NCBI GenInfo Identifier: | 3913590 |
NCBI Gene ID: | 2066 |
NCBI Accession: | |
UniProt Related Accession: | Q15303 |
Molecular Weight: | |
NCBI Full Name: | Receptor tyrosine-protein kinase erbB-4 |
NCBI Synonym Full Names: | erb-b2 receptor tyrosine kinase 4 |
NCBI Official Symbol: | ERBB4 |
NCBI Official Synonym Symbols: | HER4; ALS19; p180erbB4 |
NCBI Protein Information: | receptor tyrosine-protein kinase erbB-4 |
UniProt Protein Name: | |
UniProt Gene Name: |
Antibodies |
Anti-ERBB4 Antibody (CAB0749) |
Anti-ERBB4 Antibody (CAB6133) |
Anti-Phospho-ERBB4-Y1284 Antibody (CABP0034) |
Anti-ErbB4 Antibody (CAB19047) |
Phospho-ERBB4 (Y1284) Antibody (PACO03632) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |