ERBB4 Antibody (PACO03633)
- SKU:
- PACO03633
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ERBB4 Antibody |
抗体コード: | PACO03633 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC, IF |
推奨される希釈: | IHC:1:100-1:300, IF:1:200-1:1000 |
反応性: | Human, Mouse, Rat |
免疫原: | synthesized peptide derived from human ErbB-4 around the non-phosphorylation site of Y1284. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | ERBB4; HER4; Receptor tyrosine-protein kinase erbB-4; Proto-oncogene-like protein c-ErbB-4; Tyrosine kinase-type cell surface receptor HER4; p180erbB4 |
NCBI Summary: | This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q15303 |
NCBI GenInfo Identifier: | 3913590 |
NCBI Gene ID: | 2066 |
NCBI Accession: | |
UniProt Related Accession: | Q15303 |
Molecular Weight: | |
NCBI Full Name: | Receptor tyrosine-protein kinase erbB-4 |
NCBI Synonym Full Names: | erb-b2 receptor tyrosine kinase 4 |
NCBI Official Symbol: | ERBB4 |
NCBI Official Synonym Symbols: | HER4; ALS19; p180erbB4 |
NCBI Protein Information: | receptor tyrosine-protein kinase erbB-4 |
UniProt Protein Name: | |
UniProt Gene Name: |