ELP3 Antibody (PACO19233)
- SKU:
- PACO19233
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ELP3 Antibody (PACO19233) |
抗体コード: | PACO19233 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, IHC:1:15-1:50 |
反応性: | Human, Mouse |
免疫原: | Synthetic peptide of human ELP3 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19233(ELP3 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO19233(ELP3 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons. Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. May also have a methyltransferase activity. Involved in cell migration. |
シノニム: | elongator acetyltransferase complex subunit 3 |
UniProt Protein Function: | ELP3: a histone acetyltransferase. A subunit of the Elongator complex, which associates with the elongating, hyperphosphorylated form of RNA polymerase II. |
UniProt Protein Details: | Protein type:EC 2.3.1.48; Acetyltransferase Chromosomal Location of Human Ortholog: 8p21.1 Cellular Component: cytoplasm; Elongator holoenzyme complex; histone acetyltransferase complex; nucleolus; transcription elongation factor complex Molecular Function:H3 histone acetyltransferase activity; H4 histone acetyltransferase activity; phosphorylase kinase regulator activity; protein binding Biological Process: central nervous system development; neuron migration; positive regulation of cell migration; regulation of transcription from RNA polymerase II promoter; RNA elongation from RNA polymerase II promoter; tRNA wobble uridine modification |
NCBI Summary: | ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009] |
UniProt Code: | Q9H9T3 |
NCBI GenInfo Identifier: | 145558902 |
NCBI Gene ID: | 55140 |
NCBI Accession: | Q9H9T3.2 |
UniProt Secondary Accession: | Q9H9T3,Q53G84, Q6AWB0, Q9BVF7, Q9NVZ1, B4DE19, B4DIG1 E2QRI5, |
UniProt Related Accession: | Q9H9T3 |
Molecular Weight: | 52,202 Da |
NCBI Full Name: | Elongator complex protein 3 |
NCBI Synonym Full Names: | elongator acetyltransferase complex subunit 3 |
NCBI Official Symbol: | ELP3 |
NCBI Official Synonym Symbols: | KAT9 |
NCBI Protein Information: | elongator complex protein 3 |
UniProt Protein Name: | Elongator complex protein 3 |
Protein Family: | Elongator complex protein |
UniProt Gene Name: | ELP3 |
UniProt Entry Name: | ELP3_HUMAN |
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Anti-ELP3 Antibody (CAB9877) |
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