ELP3 Antibody, Biotin conjugated (PACO57547)
- SKU:
- PACO57547
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | ELP3 Antibody, Biotin conjugated (PACO57547) |
抗体コード: | PACO57547 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Elongator complex protein 3 protein (1-85AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in acetylation of alpha-tubulin. May also have a methyltransferase activity. Involved in cell migration. Involved in neurogenesis. Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha-tubulin acetylation. |
シノニム: | Elongator complex protein 3 (hELP3) (EC 2.3.1.48), ELP3 |
UniProt Protein Function: | ELP3: a histone acetyltransferase. A subunit of the Elongator complex, which associates with the elongating, hyperphosphorylated form of RNA polymerase II. |
UniProt Protein Details: | Protein type:EC 2.3.1.48; Acetyltransferase Chromosomal Location of Human Ortholog: 8p21.1 Cellular Component: cytoplasm; Elongator holoenzyme complex; histone acetyltransferase complex; nucleolus; transcription elongation factor complex Molecular Function:H3 histone acetyltransferase activity; H4 histone acetyltransferase activity; phosphorylase kinase regulator activity; protein binding Biological Process: central nervous system development; neuron migration; positive regulation of cell migration; regulation of transcription from RNA polymerase II promoter; RNA elongation from RNA polymerase II promoter; tRNA wobble uridine modification |
NCBI Summary: | ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009] |
UniProt Code: | Q9H9T3 |
NCBI GenInfo Identifier: | 145558902 |
NCBI Gene ID: | 55140 |
NCBI Accession: | Q9H9T3.2 |
UniProt Secondary Accession: | Q9H9T3,Q53G84, Q6AWB0, Q9BVF7, Q9NVZ1, B4DE19, B4DIG1 E2QRI5, |
UniProt Related Accession: | Q9H9T3 |
Molecular Weight: | 52,202 Da |
NCBI Full Name: | Elongator complex protein 3 |
NCBI Synonym Full Names: | elongator acetyltransferase complex subunit 3 |
NCBI Official Symbol: | ELP3 |
NCBI Official Synonym Symbols: | KAT9 |
NCBI Protein Information: | elongator complex protein 3 |
UniProt Protein Name: | Elongator complex protein 3 |
Protein Family: | Elongator complex protein |
UniProt Gene Name: | ELP3 |
UniProt Entry Name: | ELP3_HUMAN |