DNAJB1 Antibody (PACO31784)
- SKU:
- PACO31784
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | DNAJB1 Antibody (PACO31784) |
抗体コード: | PACO31784 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human DnaJ homolog subfamily B member 1 protein (1-340AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot All lanes: DNAJB1 antibody at 3µg/ml Lane 1: Mouse spleen tissue Lane 2: Colo320 whole cell lysate Lane 3: Hela whole cell lysate Lane 4: LO2 whole cell lysate Lane 5: HepG2 whole cell lysate Lane 6: HT29 whole cell lysate Lane 7: A549 whole cell lysate Lane 8: Jurkat whole cell lysate Lane 9: MCF-7 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 39, 28 kDa Observed band size: 39 kDa . | |
Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO31784 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human testis tissue using PACO31784 at dilution of 1:100. |
バックグラウンド: | Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro). |
シノニム: | DnaJ homolog subfamily B member 1 (DnaJ protein homolog 1) (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40) (Human DnaJ protein 1) (hDj-1), DNAJB1, DNAJ1 HDJ1 HSPF1 |
UniProt Protein Function: | Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. |
NCBI Summary: | This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
UniProt Code: | P25685 |
NCBI GenInfo Identifier: | 1706473 |
NCBI Gene ID: | 3337 |
NCBI Accession: | P25685.4 |
UniProt Secondary Accession: | P25685,B4DX52, |
UniProt Related Accession: | P25685 |
Molecular Weight: | 340 |
NCBI Full Name: | DnaJ homolog subfamily B member 1 |
NCBI Synonym Full Names: | DnaJ (Hsp40) homolog, subfamily B, member 1 |
NCBI Official Symbol: | DNAJB1 |
NCBI Official Synonym Symbols: | Hdj1; Sis1; HSPF1; Hsp40; RSPH16B |
NCBI Protein Information: | dnaJ homolog subfamily B member 1; human DnaJ protein 1; dnaJ protein homolog 1; radial spoke 16 homolog B; heat shock 40 kDa protein 1 |
UniProt Protein Name: | DnaJ homolog subfamily B member 1 |
UniProt Synonym Protein Names: | DnaJ protein homolog 1; Heat shock 40 kDa protein 1; HSP40; Heat shock protein 40; Human DnaJ protein 1; hDj-1 |
Protein Family: | DnaJ homolog subfamily |
UniProt Gene Name: | DNAJB1 |
UniProt Entry Name: | DNJB1_HUMAN |
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