Anti-DNAJB1 Antibody (CAB5504)[KO Validated]
- SKU:
- CAB5504
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-DNAJB1 Antibody [KO Validated] |
抗体コード: | CAB5504 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human DNAJB1 (NP_006136.1). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | 293T, MCF-7, BxPC-3, BT-474, SW620, K-562, Mouse thymus, Mouse spleen, Mouse thymus |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human DNAJB1 (NP_006136.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MGKD YYQT LGLA RGAS DEEI KRAY RRQA LRYH PDKN KEPG AEEK FKEI AEAY DVLS DPRK REIF DRYG EEGL KGSG PSGG SGGG ANGT SFSY TFHG DPHA MFAE FFGG RNPF DTFF GQRN GEEG MDID DPFS GFPM GMGG FTNV NFGR SRSA QEPA RKKQ DPPV THDL RVSL EEIY SGCT KKMK ISHK RLNP DGKS IRNE DKIL TIEV KKGW KEGT KITF PKEG DQTS NNIP ADIV FVLK DKPH NIFK RDGS DVIY PARI SLRE ALCG CTVN VPTL DGRT IPVV FKDV IRPG MRRK VPGE GLPL PKTP EKRG DLII EFEV IFPE RIPQ TSRT VLEQ VLPI |
遺伝子ID: | 3337 |
Uniprot: | P25685 |
セルラーロケーション: | Cytoplasm, Nucleus, nucleolus |
計算された分子量: | 27kDa/38kDa |
観察された分子量: | 39kDa |
同義語: | DNAJB1, HSPF1, Hdj1, Hsp40, RSPH16B, Sis1 |
バックグラウンド: | This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. |
NCBI Summary: | This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
UniProt Code: | P25685 |
NCBI GenInfo Identifier: | 1706473 |
NCBI Gene ID: | 3337 |
NCBI Accession: | P25685.4 |
UniProt Secondary Accession: | P25685,B4DX52, |
UniProt Related Accession: | P25685 |
Molecular Weight: | 340 |
NCBI Full Name: | DnaJ homolog subfamily B member 1 |
NCBI Synonym Full Names: | DnaJ (Hsp40) homolog, subfamily B, member 1 |
NCBI Official Symbol: | DNAJB1 |
NCBI Official Synonym Symbols: | Hdj1; Sis1; HSPF1; Hsp40; RSPH16B |
NCBI Protein Information: | dnaJ homolog subfamily B member 1; human DnaJ protein 1; dnaJ protein homolog 1; radial spoke 16 homolog B; heat shock 40 kDa protein 1 |
UniProt Protein Name: | DnaJ homolog subfamily B member 1 |
UniProt Synonym Protein Names: | DnaJ protein homolog 1; Heat shock 40 kDa protein 1; HSP40; Heat shock protein 40; Human DnaJ protein 1; hDj-1 |
Protein Family: | DnaJ homolog subfamily |
UniProt Gene Name: | DNAJB1 |
UniProt Entry Name: | DNJB1_HUMAN |
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