DIS3L Antibody, FITC conjugated (PACO38360)
- SKU:
- PACO38360
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | DIS3L Antibody, FITC conjugated (PACO38360) |
抗体コード: | PACO38360 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human DIS3-like exonuclease 1 protein (1-300AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. |
シノニム: | DIS3-like exonuclease 1 (EC 3.1.13.-), DIS3L, DIS3L1 KIAA1955 |
UniProt Protein Function: | DIS3L: Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. Belongs to the RNR ribonuclease family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.1.13.-; Ribonuclease Chromosomal Location of Human Ortholog: 15q22.31 Cellular Component: centrosome; cytoplasm; plasma membrane Molecular Function:protein binding; 3'-5'-exoribonuclease activity; enzyme binding; RNA binding Biological Process: rRNA catabolic process |
UniProt Code: | Q8TF46 |
NCBI GenInfo Identifier: | 219521928 |
NCBI Gene ID: | 115752 |
NCBI Accession: | NP_001137160.1 |
UniProt Secondary Accession: | Q8TF46,Q8N1N8, Q8WTU9, Q96CM7, |
UniProt Related Accession: | Q8TF46 |
Molecular Weight: | 120,787 Da |
NCBI Full Name: | DIS3-like exonuclease 1 isoform 1 |
NCBI Synonym Full Names: | DIS3 like exosome 3'-5' exoribonuclease |
NCBI Official Symbol: | DIS3L |
NCBI Official Synonym Symbols: | DIS3L1 |
NCBI Protein Information: | DIS3-like exonuclease 1; DIS3 mitotic control homolog-like |
UniProt Protein Name: | DIS3-like exonuclease 1 |
Protein Family: | DIS3-like exonuclease |
UniProt Gene Name: | DIS3L |
UniProt Entry Name: | DI3L1_HUMAN |