DAB1 (Ab-232) Antibody (PACO21406)
- SKU:
- PACO21406
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | DAB1 (Ab-232) Antibody (PACO21406) |
抗体コード: | PACO21406 |
サイズ: | 100ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:50-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Peptide sequence around aa.230~234 (G-V-Y-D-V) derived from Human Dab1. |
憲法: | Liquid |
ストレージバッファ: | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
精製方法: | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates |
抗体のクローン性: | Polyclonal |
Conjugate: | Non-conjugated |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Dab1(Ab-232) Antibody(left) or the same antibody preincubated with blocking peptide(right). |
シノニム: | Disabled homolog 1 |
UniProt Protein Function: | DAB1: an adaptor molecule functioning in neural development. The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. Thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Associates with the SH2 domains of Src, Fyn and Abl. Phosphorylated in response to reelin induction in embryonic neurons |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 1p32.2 Cellular Component: cytosol; intracellular membrane-bound organelle Molecular Function:protein binding |
NCBI Summary: | The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017] |
UniProt Code: | O75553 |
NCBI GenInfo Identifier: | 150421536 |
NCBI Gene ID: | 1600 |
NCBI Accession: | O75553.3 |
UniProt Secondary Accession: | O75553,Q4LE59, Q5T6M6, Q5T6M9, Q5T835, Q5T836, Q5T837 Q6NWS9, Q6NWT0, Q6NWT1, A4FU90, B3KTG3, |
UniProt Related Accession: | O75553 |
Molecular Weight: | 64kDa |
NCBI Full Name: | Disabled homolog 1 |
NCBI Synonym Full Names: | DAB1, reelin adaptor protein |
NCBI Official Symbol: | DAB1 |
NCBI Protein Information: | disabled homolog 1 |
UniProt Protein Name: | Disabled homolog 1 |
Protein Family: | Disabled |
UniProt Gene Name: | DAB1 |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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