CLDN12 Antibody, Biotin conjugated (PACO25784)
- SKU:
- PACO25784
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | CLDN12 Antibody, Biotin conjugated (PACO25784) |
抗体コード: | PACO25784 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Claudin-12 protein (32-87AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. |
シノニム: | Claudin-12, CLDN12 |
UniProt Protein Function: | Claudin-12: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Belongs to the claudin family. |
UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 7q21.13 Cellular Component: plasma membrane; tight junction Molecular Function:identical protein binding; protein binding Biological Process: calcium-independent cell-cell adhesion |
NCBI Summary: | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in the inner ear and bladder epithelium, and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Multiple alternatively spliced transcript variants encoding the same protein have been found.[provided by RefSeq, Sep 2011] |
UniProt Code: | P56749 |
NCBI GenInfo Identifier: | 6685308 |
NCBI Gene ID: | 9069 |
NCBI Accession: | P56749.1 |
UniProt Secondary Accession: | P56749,Q7LDZ0, D6W5Q4, |
UniProt Related Accession: | P56749 |
Molecular Weight: | 27kDa |
NCBI Full Name: | Claudin-12 |
NCBI Synonym Full Names: | claudin 12 |
NCBI Official Symbol: | CLDN12 |
NCBI Protein Information: | claudin-12 |
UniProt Protein Name: | Claudin-12 |
Protein Family: | Claudin |
UniProt Gene Name: | CLDN12 |