UniProt Protein Function: | BHLHE23: May function as transcriptional repressor. May modulate the expression of genes required for the differentiation and/or maintenance of pancreatic and neuronal cell types. May be important for rod bipolar cell maturation.Protein type: Transcription factorChromosomal Location of Human Ortholog: 20q13.33Cellular Component: nucleusMolecular Function: protein dimerization activity; DNA bindingBiological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the basic helix-loop-helix transcription factor family. Members of this family contain two highly conserved and functionally distinct domains: the basic domain targets sequence-specific DNA binding, while the helix-loop-helix domain facilitates protein interaction. Studies of a related gene in mouse suggest that the encoded protein may function as a transcriptional repressor in the pancreas and brain, and that it is required for normal retinal function. [provided by RefSeq, May 2013] |
UniProt Code: | Q8NDY6 |
NCBI GenInfo Identifier: | 506326971 |
NCBI Gene ID: | 128408 |
NCBI Accession: | NP_542173.2 |
UniProt Secondary Accession: | Q8NDY6,B2RP69 |
UniProt Related Accession: | Q8NDY6 |
Molecular Weight: | 23,665 Da |
NCBI Full Name: | class E basic helix-loop-helix protein 23 |
NCBI Synonym Full Names: | basic helix-loop-helix family, member e23 |
NCBI Official Symbol: | BHLHE23 |
NCBI Official Synonym Symbols: | BETA4; BHLHB4; bA305P22.3 |
NCBI Protein Information: | class E basic helix-loop-helix protein 23; class B basic helix-loop-helix protein 4; basic helix-loop-helix domain containing, class B, 4 |
UniProt Protein Name: | Class E basic helix-loop-helix protein 23 |
UniProt Synonym Protein Names: | Class B basic helix-loop-helix protein 4; bHLHb4 |
Protein Family: | Class E basic helix-loop-helix protein |
UniProt Gene Name: | BHLHE23 |
UniProt Entry Name: | BHE23_HUMAN |