CHML Antibody, FITC conjugated (PACO63637)
- SKU:
- PACO63637
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | CHML Antibody, FITC conjugated (PACO63637) |
抗体コード: | PACO63637 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Rab proteins geranylgeranyltransferase component A 2 protein (480-656AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family. |
シノニム: | Rab proteins geranylgeranyltransferase component A 2 (Choroideremia-like protein) (Rab escort protein 2) (REP-2), CHML, REP2 |
UniProt Protein Function: | CHML: Binds unprenylated Rab proteins, presents it to the catalytic Rab GGTase dimer, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than REP-1 in supporting prenylation of Rab3 family. Belongs to the Rab GDI family.Chromosomal Location of Human Ortholog: 1q43Cellular Component: cytoplasm; nucleoplasm; Rab-protein geranylgeranyltransferase complexMolecular Function: Rab GTPase bindingBiological Process: protein geranylgeranylation |
UniProt Protein Details: | |
NCBI Summary: | The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissues other than retina. CHML is localized close to the gene for Usher syndrome type II. [provided by RefSeq, Jul 2008] |
UniProt Code: | P26374 |
NCBI GenInfo Identifier: | 47117837 |
NCBI Gene ID: | 1122 |
NCBI Accession: | P26374.2 |
UniProt Secondary Accession: | P26374,Q17RE0, Q9H1Y4, B2RAB9 |
UniProt Related Accession: | P26374 |
Molecular Weight: | 74,071 Da |
NCBI Full Name: | Rab proteins geranylgeranyltransferase component A 2 |
NCBI Synonym Full Names: | CHM like, Rab escort protein 2 |
NCBI Official Symbol: | CHML |
NCBI Official Synonym Symbols: | REP2 |
NCBI Protein Information: | rab proteins geranylgeranyltransferase component A 2 |
UniProt Protein Name: | Rab proteins geranylgeranyltransferase component A 2 |
UniProt Synonym Protein Names: | Choroideremia-like protein; Rab escort protein 2; REP-2 |
Protein Family: | Rab proteins geranylgeranyltransferase component |
UniProt Gene Name: | CHML |
UniProt Entry Name: | RAE2_HUMAN |