CD109 Antibody, FITC conjugated (PACO55968)
- SKU:
- PACO55968
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | CD109 Antibody, FITC conjugated (PACO55968) |
抗体コード: | PACO55968 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human CD109 antigen protein (967-1122AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Modulates negatively TGFB1 signaling in keratinocytes. |
シノニム: | CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109), CD109, CPAMD7 |
UniProt Protein Function: | CD109: Modulates negatively TGFB1 signaling in keratinocytes. Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, GPI anchor Chromosomal Location of Human Ortholog: 6q13 Cellular Component: extracellular space; cell surface; plasma membrane Molecular Function:serine-type endopeptidase inhibitor activity; transforming growth factor beta binding Biological Process: hair follicle development; negative regulation of protein amino acid phosphorylation; negative regulation of transforming growth factor beta receptor signaling pathway; regulation of keratinocyte differentiation |
NCBI Summary: | This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014] |
UniProt Code: | Q6YHK3 |
NCBI GenInfo Identifier: | 117949389 |
NCBI Gene ID: | 135228 |
NCBI Accession: | Q6YHK3.2 |
UniProt Related Accession: | Q6YHK3 |
Molecular Weight: | |
NCBI Full Name: | CD109 antigen |
NCBI Synonym Full Names: | CD109 molecule |
NCBI Official Symbol: | CD109 |
NCBI Official Synonym Symbols: | p180; r150; CPAMD7 |
NCBI Protein Information: | CD109 antigen |
UniProt Protein Name: | CD109 antigen |
UniProt Synonym Protein Names: | 150 kDa TGF-beta-1-binding protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; Platelet-specific Gov antigen; p180; r150 |
Protein Family: | CD109 antigen |
UniProt Gene Name: | CD109 |
UniProt Entry Name: | CD109_HUMAN |