BHLHE41 Antibody (PACO05359)
- SKU:
- PACO05359
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | BHLHE41 Antibody (PACO05359) |
抗体コード: | PACO05359 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:40000, WB:1:500-1:2000, IHC:1:100-1:300 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthesized peptide derived from the N-terminal region of human 40879. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | BHLHE41; BHLHB3; DEC2; SHARP1; Class E basic helix-loop-helix protein 41; bHLHe41; Class B basic helix-loop-helix protein 3; bHLHb3; Differentially expressed in chondrocytes protein 2; hDEC2; Enhancer-of-split and hairy-related protein 1; S |
UniProt Protein Function: | BHLHB3: May be a transcriptional repressor that represses both basal and activated transcription. Homodimerize. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 12p12.1 Molecular Function:bHLH transcription factor binding; histone deacetylase binding; MRF binding; protein binding; protein heterodimerization activity; protein homodimerization activity; RNA polymerase II transcription factor activity, enhancer binding; transcription corepressor activity Biological Process: negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent Disease: Short Sleeper |
NCBI Summary: | This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. Defects in this gene are associated with the short sleep phenotype. [provided by RefSeq, Feb 2014] |
UniProt Code: | Q9C0J9 |
NCBI GenInfo Identifier: | 20137459 |
NCBI Gene ID: | 79365 |
NCBI Accession: | Q9C0J9.1 |
UniProt Secondary Accession: | Q9C0J9,A2I2N8, |
UniProt Related Accession: | Q9C0J9 |
Molecular Weight: | 50kDa |
NCBI Full Name: | Class E basic helix-loop-helix protein 41 |
NCBI Synonym Full Names: | basic helix-loop-helix family member e41 |
NCBI Official Symbol: | BHLHE41 |
NCBI Official Synonym Symbols: | DEC2; hDEC2; BHLHB3; SHARP1 |
NCBI Protein Information: | class E basic helix-loop-helix protein 41 |
UniProt Protein Name: | Class E basic helix-loop-helix protein 41 |
UniProt Synonym Protein Names: | Class B basic helix-loop-helix protein 3; bHLHb3; Differentially expressed in chondrocytes protein 2; hDEC2; Enhancer-of-split and hairy-related protein 1; SHARP-1 |
Protein Family: | Class E basic helix-loop-helix protein |
UniProt Gene Name: | BHLHE41 |